{"id":"W4389232322","doi":"10.1182/blood-2023-188721","title":"Oligomannose-Type Glycans in the Antigen Binding Site Identify Origin and Prognosis of Diffuse Large B Cell Lymphoma","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"Diffuse large B-cell lymphoma; Biology; Germinal center; IGHV@; Follicular lymphoma; Lymphoma; Cancer research; Immunology; Antibody; Molecular biology; B cell; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000914283,0.0003277273,0.0006303065,0.0007602304,0.0004885091,0.001083247,0.0005376744,0.0005022319,0.001745102],"category_scores_gemma":[0.001640901,0.0002091406,0.0005144983,0.0009041085,0.0002761911,0.0003072977,0.000980393,0.000595042,0.000621596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003594201,"about_ca_system_score_gemma":0.0004346498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004051801,"about_ca_topic_score_gemma":0.005949363,"domain_scores_codex":[0.9995899,0.00006288313,0.00002982498,0.0001844041,0.00005686524,0.00007622804],"domain_scores_gemma":[0.9994067,0.0001230139,0.0001267637,0.0001401396,0.0001054071,0.00009798238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001615232,0.00007839626,0.9668875,0.000169024,0.0005907316,0.0001752827,0.0001190808,0.00102371,0.009868531,0.0001156721,0.004597211,0.0147596],"study_design_scores_gemma":[0.0001843117,0.0001992136,0.9762359,0.00008940246,0.0009447588,0.00106259,0.0002949385,0.006470731,0.003509915,0.0006466123,0.0103304,0.00003127577],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811403,0.001732307,0.001240059,0.000154395,0.00002353519,0.00001959735,0.01485648,0.00008448508,0.0007489226],"genre_scores_gemma":[0.9633538,0.0003894775,0.0008876585,0.0001213872,0.00001937926,0.00002405473,0.03478313,0.00004093811,0.0003802532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004051801,"threshold_uncertainty_score":0.008056462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01919402398091923,"score_gpt":0.2971355280172155,"score_spread":0.2779415040362963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}