{"id":"W4389233430","doi":"10.1182/blood-2023-191113","title":"Is Allogeneic Hematopoietic Stem Cell Transplant (HCT) in First Remission Beneficial to Acute Myeloid Leukemia (AML) Patients with Isocitrate Dehydrogenase(IDH) Mutations?","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Princess Margaret Cancer Centre; University of British Columbia; University Health Network","funders":"","keywords":"IDH2; Isocitrate dehydrogenase; IDH1; Oncology; Myeloid leukemia; Medicine; Hematopoietic stem cell transplantation; Internal medicine; Transplantation; Stem cell; Leukemia; Myeloid; Mutation; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00104067,0.00008871014,0.0005112299,0.0003715501,0.0001199903,0.0003505206,0.0002281766,0.0003798874,0.001884235],"category_scores_gemma":[0.003998852,0.0000470009,0.0004412424,0.0005498173,0.0003148796,0.0003235953,0.0001941985,0.000322336,0.0001604073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002672784,"about_ca_system_score_gemma":0.0004695701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005355845,"about_ca_topic_score_gemma":0.00114054,"domain_scores_codex":[0.9993942,0.0003110591,0.00007090293,0.00007636306,0.00008742028,0.00006009906],"domain_scores_gemma":[0.9985034,0.0006194233,0.0004947559,0.00005810054,0.0001094916,0.0002147455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02424804,0.0007836026,0.2456297,0.002365597,0.000722404,0.0007185774,0.0001748006,0.001431571,0.001662262,0.001211541,0.003624971,0.7174269],"study_design_scores_gemma":[0.002618326,0.01661234,0.9345772,0.002021939,0.002308201,0.003540326,0.0006818169,0.002462339,0.001656246,0.003920911,0.02954645,0.00005390646],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8835162,0.09935495,0.001634933,0.009134137,0.001507009,0.0001059938,0.0006464776,0.00004040697,0.004059963],"genre_scores_gemma":[0.9832427,0.01384165,0.0004151313,0.0007930314,0.001073522,0.00003368717,0.0003039775,0.000004783966,0.00029153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001884235,"threshold_uncertainty_score":0.00630337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01383324604880266,"score_gpt":0.2526175479280149,"score_spread":0.2387843018792123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}