{"id":"W4389233642","doi":"10.1182/blood-2023-188008","title":"Identification of Novel Transcripts and Potential Therapeutic Targets for Acute Leukemia","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Leukemia; Biology; Myeloid leukemia; Gene; Transcriptome; Acute leukemia; Computational biology; Human genome; Genome; Genetics; Cancer research; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038135,0.0003323979,0.0004350118,0.0003966913,0.0002218198,0.0005267941,0.0002068048,0.0003712858,0.002113224],"category_scores_gemma":[0.0002601577,0.0001946095,0.0003534058,0.0003895058,0.0001659759,0.0002742684,0.0002623946,0.0006585785,0.0007111371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003657054,"about_ca_system_score_gemma":0.0002779819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001606974,"about_ca_topic_score_gemma":0.0003565219,"domain_scores_codex":[0.9998536,0.00001587887,0.000008807142,0.00004008221,0.00005133769,0.00003021628],"domain_scores_gemma":[0.9998959,0.00002607663,0.00003096177,0.00000735551,0.00002112672,0.00001854758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002931661,0.00007956303,0.003554975,0.0004492395,0.00002654242,0.0002215917,0.00006521997,0.0009204056,0.9377911,0.0006542308,0.001519518,0.05442449],"study_design_scores_gemma":[0.0002717732,0.001564872,0.03578097,0.0002209258,0.0003388361,0.002048924,0.00038707,0.02138824,0.8307862,0.003239246,0.1039279,0.00004515743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9064154,0.04230505,0.03580842,0.001950615,0.0003537362,0.0003768498,0.004740233,0.00108806,0.00696168],"genre_scores_gemma":[0.9307349,0.02332396,0.03178043,0.001252395,0.0001728572,0.0004729429,0.006571754,0.0001750704,0.005515649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002113224,"threshold_uncertainty_score":0.007069409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01525198697284601,"score_gpt":0.2726917084927368,"score_spread":0.2574397215198908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}