{"id":"W4389233815","doi":"10.1371/journal.ppat.1011832","title":"The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes","year":2023,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Queen's University; Canada Foundation for Innovation","keywords":"Nucleoplasm; Cytoplasm; Capsid; Herpes simplex virus; Nuclear pore; Biology; Cell biology; Genome; Nuclear transport; Virology; Viral replication; Gene; Virus; Mutant; Cell nucleus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003639733,0.0005696923,0.0005702524,0.0002397157,0.0003557442,0.00116977,0.0005925447,0.0005178943,0.002340699],"category_scores_gemma":[0.0006121163,0.0003836245,0.0006089755,0.0001954985,0.0006485556,0.0007458051,0.0006111361,0.000685123,0.0008793343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005854897,"about_ca_system_score_gemma":0.0005362056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005596408,"about_ca_topic_score_gemma":0.0005443349,"domain_scores_codex":[0.999509,0.00007946891,0.00009209988,0.00009640144,0.0001232376,0.0000998078],"domain_scores_gemma":[0.9994454,0.0000949528,0.0002128805,0.0001174956,0.00005355862,0.00007565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002818665,0.00005069585,0.0009567082,0.0001619289,0.00003055857,0.0001748167,0.00006516756,0.0002459426,0.9893258,0.00130577,0.000128381,0.007272386],"study_design_scores_gemma":[0.00002604322,0.0001992218,0.002965644,0.00001544983,0.00001790923,0.0006062508,0.00002676498,0.0005035475,0.9859554,0.0001669091,0.009508502,0.000008407716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97855,0.007889533,0.009134859,0.0001894712,0.0001679297,0.00007254868,0.0004952609,0.0002185841,0.003281825],"genre_scores_gemma":[0.9831941,0.002575524,0.006952359,0.00006212528,0.00002009728,0.0000685759,0.0007169377,0.00005789476,0.006352553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002340699,"threshold_uncertainty_score":0.007830441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130286902317854,"score_gpt":0.2716196525752048,"score_spread":0.2403167835520263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}