{"id":"W4389233815","doi":"10.1371/journal.ppat.1011832","title":"The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes","year":2023,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Queen's University; Canada Foundation for Innovation","keywords":"Nucleoplasm; Cytoplasm; Capsid; Herpes simplex virus; Nuclear pore; Biology; Cell biology; Genome; Nuclear transport; Virology; Viral replication; Gene; Virus; Mutant; Cell nucleus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195589,0.0001989857,0.0002622375,0.00006406637,0.000751728,0.00005965241,0.00007403114,0.00008826765,0.0002678074],"category_scores_gemma":[0.00007760567,0.000133211,0.0001004541,0.0002230897,0.0001035879,0.00005093701,0.0001587411,0.0001197057,0.0003497648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001163567,"about_ca_system_score_gemma":0.00003375071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004412527,"about_ca_topic_score_gemma":0.0005551536,"domain_scores_codex":[0.99871,0.00007615413,0.0002420439,0.0003362457,0.0002620367,0.000373491],"domain_scores_gemma":[0.9991911,0.0001252647,0.00007485589,0.0003947617,0.00004891252,0.0001651043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004943006,0.002545533,0.06206802,0.0002586727,0.003219142,0.002326131,0.005910264,0.00002902117,0.2640138,0.001236083,0.007643139,0.6502559],"study_design_scores_gemma":[0.002501684,0.0005121546,0.1519064,0.0003246466,0.0007619361,0.0001072817,0.0007844651,0.002044521,0.03765752,0.001671155,0.8012077,0.0005205618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963422,0.0002936458,0.000003307262,0.0006565663,0.00008439536,0.0007956095,0.000334027,0.0002463517,0.001243934],"genre_scores_gemma":[0.9976647,0.0004321005,0.0002123621,0.0001571348,0.0001742442,0.0001196609,0.0001654587,0.00005770358,0.001016631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7935646,"threshold_uncertainty_score":0.578176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130286902317854,"score_gpt":0.2716196525752048,"score_spread":0.2403167835520263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}