{"id":"W4389235359","doi":"10.1182/blood-2023-179375","title":"Rituximab Combined with Chemotherapy and Acalabrutinib Prior to Autologous Stem Cell Transplantation in Mantle Cell Lymphoma: The Rectangle Trial","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Queen Elizabeth II Health Sciences Centre; Sunnybrook Health Science Centre; Hôpital de l'Enfant-Jésus; Princess Margaret Cancer Centre; Centre hospitalier universitaire de Québec; Health Sciences Centre; McMaster University; Spinal Cord Injury BC","funders":"","keywords":"Mantle cell lymphoma; Ibrutinib; Medicine; Rituximab; Internal medicine; Transplantation; Oncology; Autologous stem-cell transplantation; Chemotherapy regimen; Diffuse large B-cell lymphoma; Surgery; Chemotherapy; Lymphoma; Leukemia; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001483718,0.0006686428,0.001267022,0.0002489207,0.0002445616,0.001011959,0.0007377473,0.0006944057,0.002618961],"category_scores_gemma":[0.0008180286,0.0002493247,0.0009596554,0.0004659545,0.0006490716,0.0005799314,0.0003671868,0.001839892,0.0006006308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001009504,"about_ca_system_score_gemma":0.001204824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001975853,"about_ca_topic_score_gemma":0.004453935,"domain_scores_codex":[0.999435,0.0003260219,0.00002684857,0.00008655328,0.000048714,0.00007683093],"domain_scores_gemma":[0.9996231,0.00007428545,0.00009591722,0.00003910688,0.00002164541,0.0001458983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.838859,0.005477624,0.005561441,0.00160593,0.002536211,0.0001927322,0.0001394494,0.002811707,0.007182164,0.001009188,0.005922997,0.1287016],"study_design_scores_gemma":[0.8529791,0.1199868,0.01171004,0.0002967257,0.001793441,0.0002699426,0.000079522,0.001059479,0.0009689278,0.0004355795,0.0103819,0.0000384657],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.956252,0.03073001,0.0006223574,0.001433039,0.0004039901,0.001344108,0.0018567,0.0001332026,0.007224579],"genre_scores_gemma":[0.9809673,0.008896731,0.001013009,0.001688745,0.0004330662,0.001442287,0.002371153,0.00001879398,0.003168981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002618961,"threshold_uncertainty_score":0.008761346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01118403533087325,"score_gpt":0.2368391113121608,"score_spread":0.2256550759812876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}