{"id":"W4389237505","doi":"10.1002/slct.202301394","title":"Synthesis and Anticancer Activity of 1‐(Ethyl/Methyl)‐7‐( <i>p</i> ‐Methoxybenzyl Amino) and 7‐Amino‐6‐Fluoroquinolone‐Boron Difluoride Complexes","year":2023,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Substituent; Chemistry; Boron; Quinolone; Stereochemistry; Proton NMR; Nitro; Organic chemistry; Biochemistry; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002676959,0.0002616374,0.0003631462,0.00004773114,0.00009852007,0.00002826143,0.0001719531,0.000214154,0.00001880589],"category_scores_gemma":[0.0001231798,0.0002664292,0.00008768171,0.000209297,0.0002374821,0.000006522844,0.0001940433,0.0001311677,0.000001822835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002070554,"about_ca_system_score_gemma":0.00007618206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006961143,"about_ca_topic_score_gemma":0.00002002971,"domain_scores_codex":[0.9986209,0.00004498378,0.0002157271,0.0005542272,0.0001754013,0.0003887304],"domain_scores_gemma":[0.9991673,0.0001011678,0.0001326461,0.0003933462,0.00008052035,0.0001250649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000114781,0.00003498983,0.0007794617,0.0001652589,0.0001107403,0.000002619404,0.000053775,0.000002035452,0.968366,0.00003450168,0.0003224293,0.03001338],"study_design_scores_gemma":[0.0004253167,0.0001464028,0.005094714,0.00003535321,0.00007656171,0.00001924557,0.00006059132,0.00008617924,0.9895905,0.0001554874,0.00402113,0.0002885348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996681,0.002070067,0.0003338686,0.000140191,0.00007698024,0.0001458618,0.0001055687,0.00003738057,0.0004090451],"genre_scores_gemma":[0.9954145,0.003452231,0.000422756,0.00007512724,0.0001470206,0.00004637127,0.00003870107,0.00004092529,0.0003623516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02972485,"threshold_uncertainty_score":0.9999788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909698889630825,"score_gpt":0.2735684689157001,"score_spread":0.2544714800193918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}