{"id":"W4389237505","doi":"10.1002/slct.202301394","title":"Synthesis and Anticancer Activity of 1‐(Ethyl/Methyl)‐7‐( <i>p</i> ‐Methoxybenzyl Amino) and 7‐Amino‐6‐Fluoroquinolone‐Boron Difluoride Complexes","year":2023,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Substituent; Chemistry; Boron; Quinolone; Stereochemistry; Proton NMR; Nitro; Organic chemistry; Biochemistry; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008727142,0.0003080349,0.0002012276,0.0001372174,0.0001064163,0.0001351959,0.0002869914,0.0002325442,0.0007710385],"category_scores_gemma":[0.00009939877,0.0001039036,0.00009939242,0.00010339,0.000114061,0.000125108,0.0001198149,0.0001466132,0.0002573313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000264621,"about_ca_system_score_gemma":0.000151407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006831501,"about_ca_topic_score_gemma":0.0007881352,"domain_scores_codex":[0.999925,0.00001634738,0.000005903887,0.00001315733,0.00002059086,0.00001890906],"domain_scores_gemma":[0.9999565,0.000004945058,0.00001387946,0.000003138995,0.000007846753,0.00001374767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002050977,0.00002954145,0.0001033102,0.0001367594,0.000007579381,0.00007155884,0.00001630506,0.0002846793,0.9949414,0.0002756482,0.0001319099,0.003796222],"study_design_scores_gemma":[0.00007731174,0.000489331,0.0009939106,0.000008489894,0.00001358468,0.0001948685,0.000009478716,0.000705358,0.9934962,0.0000390556,0.003962066,0.0000102472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763872,0.008219386,0.006870724,0.0001647874,0.00005725991,0.00009877983,0.0006043029,0.000139869,0.00745762],"genre_scores_gemma":[0.9935864,0.001360909,0.003158589,0.00004313162,0.000008880847,0.00003507415,0.0002276257,0.00001088646,0.001568526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007710385,"threshold_uncertainty_score":0.002579391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909698889630825,"score_gpt":0.2735684689157001,"score_spread":0.2544714800193918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}