{"id":"W4389239891","doi":"10.1158/2326-6074.tumimm23-b030","title":"Abstract B030: Characterizing MAIT cells in lung cancer: Insights from NSCLC and murine models","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Granzyme B; Cytotoxic T cell; Granzyme; Immune system; Biology; T-cell receptor; Cancer research; Ex vivo; Tumor microenvironment; Immunology; Lung cancer; T cell; In vivo; Immunotherapy; CD8; Pathology; Medicine; In vitro; Perforin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004062953,0.000611308,0.0002681015,0.000896565,0.0002668737,0.0003051752,0.0002707367,0.0005050053,0.001308547],"category_scores_gemma":[0.0001401921,0.000161649,0.0003030612,0.00026087,0.0003235592,0.0003731912,0.0003334259,0.000796262,0.000589563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003367579,"about_ca_system_score_gemma":0.0001954832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004590162,"about_ca_topic_score_gemma":0.0006392231,"domain_scores_codex":[0.9997544,0.00004243791,0.00002627798,0.00005037532,0.00006347471,0.00006306525],"domain_scores_gemma":[0.999881,0.00001800076,0.00002635698,0.00001512189,0.00001687981,0.0000425986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002999905,0.0001424578,0.001481735,0.00007254774,0.000004539113,0.0001283493,0.0000294048,0.0000594216,0.9957552,0.00006574588,0.000047496,0.00191316],"study_design_scores_gemma":[0.0001088214,0.003974,0.0381065,0.00005139349,0.00005772768,0.004018758,0.0001585717,0.002008547,0.9468465,0.0001802935,0.004477006,0.00001205709],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904131,0.003275502,0.003310556,0.0001377173,0.0000249957,0.0001745854,0.0007987217,0.00008929853,0.001775534],"genre_scores_gemma":[0.9900462,0.002007631,0.003811251,0.0001003349,0.00002572483,0.0001731993,0.001761204,0.00002323783,0.002051265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001308547,"threshold_uncertainty_score":0.004377544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05391378213233809,"score_gpt":0.3382651749986699,"score_spread":0.2843513928663318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}