{"id":"W4389239891","doi":"10.1158/2326-6074.tumimm23-b030","title":"Abstract B030: Characterizing MAIT cells in lung cancer: Insights from NSCLC and murine models","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Granzyme B; Cytotoxic T cell; Granzyme; Immune system; Biology; T-cell receptor; Cancer research; Ex vivo; Tumor microenvironment; Immunology; Lung cancer; T cell; In vivo; Immunotherapy; CD8; Pathology; Medicine; In vitro; Perforin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004252894,0.0002394861,0.0004063812,0.000806396,0.0003823412,0.00005036844,0.0003403407,0.0004868318,0.002857858],"category_scores_gemma":[0.00004676756,0.0002315621,0.00006550265,0.0006700699,0.0004440043,0.0004066723,0.0003398881,0.001629755,0.0008624016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003148478,"about_ca_system_score_gemma":0.0002037163,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008515343,"about_ca_topic_score_gemma":0.0005408094,"domain_scores_codex":[0.9976102,0.0003856413,0.0004461808,0.000629873,0.00009022866,0.0008379255],"domain_scores_gemma":[0.998865,0.0004111515,0.0001050016,0.0003993695,0.0001851729,0.00003432057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007134143,0.00006579253,0.001370372,0.00003908511,0.0002574394,0.00002694042,0.001420719,0.00005095391,0.9734275,0.0001811828,0.00924656,0.01320005],"study_design_scores_gemma":[0.004992379,0.0002164096,0.210748,0.0006923597,0.0000398116,0.00001975125,0.00266452,0.0009421086,0.5809271,0.0007885662,0.1972715,0.000697552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9556586,0.03672829,0.00001033057,0.001162291,0.004279478,0.0004066049,0.00004584286,0.0001352231,0.001573337],"genre_scores_gemma":[0.9633489,0.02603701,0.000006007644,0.0001618607,0.0001044578,0.0004173479,0.0002419755,0.00004161556,0.009640826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3925004,"threshold_uncertainty_score":0.9999155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05391378213233809,"score_gpt":0.3382651749986699,"score_spread":0.2843513928663318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}