{"id":"W4389240415","doi":"10.1158/2326-6074.tumimm23-b041","title":"Abstract B041: Defining the Determinants of Immune Response in DNA Homologous Recombination Deficient Tumors","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immune checkpoint; CXCL10; Tumor microenvironment; Immune system; Immunotherapy; Cancer research; Chemokine; CXCR3; Cancer immunotherapy; Biology; Cancer; Immunology; Chemokine receptor; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002320912,0.0003139264,0.0002116265,0.0004828971,0.000135493,0.0003434183,0.0002050652,0.0003838933,0.002085853],"category_scores_gemma":[0.0001343954,0.0001444482,0.0002148687,0.000170129,0.0002211539,0.0001604496,0.0002078211,0.0008172577,0.0007172662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004726546,"about_ca_system_score_gemma":0.0001480856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005348113,"about_ca_topic_score_gemma":0.0005680256,"domain_scores_codex":[0.9997211,0.00004779161,0.00002325943,0.00006397481,0.00007879805,0.00006507088],"domain_scores_gemma":[0.999843,0.0000214042,0.00005777569,0.00001219021,0.00001728647,0.00004823957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007762136,0.00001943269,0.0002311651,0.000008057074,0.000001177289,0.000008412001,0.000004500267,0.00004787028,0.9991049,0.00003816708,0.00002779554,0.0004308177],"study_design_scores_gemma":[0.00002024867,0.0005979636,0.01146766,0.00000787923,0.000009309048,0.0002968274,0.00004356001,0.00210556,0.983503,0.00006735996,0.001873923,0.000006707037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917691,0.0005290819,0.00481501,0.0001079886,0.00001966398,0.00005011662,0.001344637,0.0001136043,0.001250908],"genre_scores_gemma":[0.9896469,0.0002535799,0.004637054,0.0001081332,0.000008529322,0.00007648739,0.002012957,0.00008167937,0.003174694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002085853,"threshold_uncertainty_score":0.006977916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06969010939385277,"score_gpt":0.4038660274973204,"score_spread":0.3341759181034676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}