{"id":"W4389240426","doi":"10.1158/2326-6074.tumimm23-b004","title":"Abstract B004: Neoantigen adenoviral cancer vaccine generates improved CD8+ T-cell responses compared to adjuvanted peptide vaccine","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Peptide vaccine; Immune system; CD8; Immunology; Cancer vaccine; T cell; Cancer immunotherapy; Vaccination; Epitope; Virology; Immunotherapy; Biology; Antigen; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008912231,0.0004012352,0.0001960877,0.0001692648,0.00006706154,0.0001937192,0.0001597187,0.0002725389,0.004092372],"category_scores_gemma":[0.0000794867,0.00008605496,0.0001478465,0.0001234088,0.0001108553,0.0001333635,0.0001016719,0.0005043835,0.0007959931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309764,"about_ca_system_score_gemma":0.0001719822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003930008,"about_ca_topic_score_gemma":0.0002993074,"domain_scores_codex":[0.9999106,0.00001064825,0.000008697813,0.0000168299,0.00003064183,0.00002262734],"domain_scores_gemma":[0.9999422,0.000008741912,0.00001315882,0.000006971176,0.00001174261,0.00001720775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001279172,0.00004930952,0.00008175888,0.00003529633,0.000002631568,0.00001149529,0.000004301769,0.0001029294,0.9980568,0.00004545583,0.00008615757,0.001396017],"study_design_scores_gemma":[0.0000279701,0.000904004,0.001228498,0.000005719921,0.000009807929,0.0001098608,0.000006976686,0.0007183516,0.9942381,0.00002692386,0.00272133,0.00000243742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909739,0.001054768,0.003902987,0.0001228064,0.0001062557,0.00007173132,0.0007897462,0.0001690775,0.002808688],"genre_scores_gemma":[0.9840719,0.0004544551,0.004777199,0.00005642297,0.00001908219,0.00004642795,0.001816209,0.00004555431,0.008712646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004092372,"threshold_uncertainty_score":0.01369035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06228367985435414,"score_gpt":0.3741527830259748,"score_spread":0.3118691031716207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}