{"id":"W4389241389","doi":"10.1158/2326-6074.tumimm23-b002","title":"Abstract B002: Vidutolimod, an immunostimulatory virus-like particle, reduces proliferation but enhances the activation of tumor-specific T cells","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tumor microenvironment; T cell; CD8; Biology; Population; Immune system; Cytotoxic T cell; Splenocyte; Cancer research; Molecular biology; Immunology; Medicine; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002491178,0.0003182694,0.0004789553,0.0004465526,0.001184167,0.00007711225,0.001075448,0.0003922051,0.001301934],"category_scores_gemma":[0.0001818815,0.0002434535,0.0001499333,0.001164479,0.002133861,0.000555083,0.0002226588,0.001241004,0.0009951288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001615403,"about_ca_system_score_gemma":0.0005380189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006536224,"about_ca_topic_score_gemma":0.00002885243,"domain_scores_codex":[0.9955859,0.001731018,0.0007577567,0.0006041169,0.0002359731,0.001085306],"domain_scores_gemma":[0.9967031,0.001362324,0.000297101,0.00102208,0.0005861067,0.00002928761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003337183,0.0002418579,0.0001881097,0.00003131082,0.0003918635,0.000004649348,0.002428001,0.00009891521,0.9756644,0.0003088421,0.002528289,0.01477662],"study_design_scores_gemma":[0.001125277,0.0005152875,0.04163277,0.0001028265,0.00001377967,0.00001244819,0.002517601,0.00002485843,0.9310023,0.0001542842,0.02266111,0.0002375126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713728,0.02522741,0.00001024346,0.0006902423,0.001448922,0.0008571847,0.00005866124,0.0001706825,0.0001638598],"genre_scores_gemma":[0.987645,0.008982325,0.000007851715,0.00009759305,0.0001043241,0.0005232078,0.0001120183,0.00005500954,0.002472685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04466212,"threshold_uncertainty_score":0.9997827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07310221273367039,"score_gpt":0.3595919720579775,"score_spread":0.2864897593243071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}