{"id":"W4389241389","doi":"10.1158/2326-6074.tumimm23-b002","title":"Abstract B002: Vidutolimod, an immunostimulatory virus-like particle, reduces proliferation but enhances the activation of tumor-specific T cells","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tumor microenvironment; T cell; CD8; Biology; Population; Immune system; Cytotoxic T cell; Splenocyte; Cancer research; Molecular biology; Immunology; Medicine; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001177175,0.0003325352,0.0001911076,0.0002261947,0.00009160836,0.0002187813,0.0002730836,0.0005099581,0.003451588],"category_scores_gemma":[0.0001047163,0.00009374251,0.0001682305,0.0001162989,0.0001539354,0.000171644,0.00008375441,0.0006420815,0.0007093307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001906393,"about_ca_system_score_gemma":0.0001711392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004577397,"about_ca_topic_score_gemma":0.0003198528,"domain_scores_codex":[0.9999148,0.0000145359,0.000006077859,0.00001677747,0.0000222782,0.0000256008],"domain_scores_gemma":[0.9999399,0.00001571482,0.00001273482,0.00000580915,0.000006772059,0.00001902788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001067983,0.0002609747,0.0001550357,0.0000824826,0.000006064709,0.0000412114,0.000008574196,0.00007575015,0.9929548,0.00009885591,0.0003448433,0.004903638],"study_design_scores_gemma":[0.0001739256,0.004453508,0.002455159,0.00001085996,0.00001729521,0.000242576,0.00001215552,0.0007202302,0.9880399,0.00003371406,0.003837302,0.000003269058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881811,0.002649221,0.002676977,0.0002044887,0.0001730287,0.00007367724,0.0006799964,0.0002120797,0.005149464],"genre_scores_gemma":[0.9877246,0.0007888043,0.002329748,0.0001461481,0.00005751804,0.00006909356,0.001255882,0.00003705606,0.007591151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003451588,"threshold_uncertainty_score":0.01154673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07310221273367039,"score_gpt":0.3595919720579775,"score_spread":0.2864897593243071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}