{"id":"W4389241393","doi":"10.1158/2326-6074.tumimm23-a030","title":"Abstract A030: Blood-based screening panel for lung cancer based on clonal hematopoietic mutations in tumor infiltrating immune cells","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lung cancer; Cancer; Immune system; Medicine; Circulating tumor cell; Somatic evolution in cancer; Haematopoiesis; Immunology; Oncology; Cancer research; Internal medicine; Biology; Metastasis; Stem cell; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001474553,0.0006019527,0.0005065717,0.001614294,0.0002080483,0.0006585104,0.0004459613,0.0005571566,0.002115835],"category_scores_gemma":[0.003070571,0.0001564657,0.0004746841,0.000696216,0.0001562388,0.0002018307,0.0002889773,0.0005210465,0.001043331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003430827,"about_ca_system_score_gemma":0.0003156971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002183279,"about_ca_topic_score_gemma":0.002392954,"domain_scores_codex":[0.9990388,0.0003193438,0.00009586335,0.0001894628,0.0002802875,0.00007627696],"domain_scores_gemma":[0.9982374,0.0007998481,0.0002778951,0.00008301952,0.0004320414,0.0001697991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001715466,0.0003807118,0.8082403,0.0001226949,0.0001640165,0.0006813315,0.00005734375,0.005012348,0.1259138,0.000202589,0.005329343,0.05218011],"study_design_scores_gemma":[0.0001519439,0.001761748,0.7070404,0.00007528443,0.0002874076,0.003649824,0.0001084837,0.1228267,0.1573992,0.0005878063,0.006047541,0.00006379588],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639906,0.00107677,0.02423814,0.0005439266,0.00007069553,0.0002051567,0.005557128,0.0009764459,0.003341163],"genre_scores_gemma":[0.9835624,0.0001170212,0.0122226,0.0002112234,0.00002812218,0.00007525628,0.002637306,0.00002897785,0.001116997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002183279,"threshold_uncertainty_score":0.007798314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0600768943612152,"score_gpt":0.3735269915377564,"score_spread":0.3134500971765412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}