{"id":"W4389241441","doi":"10.1158/2326-6074.tumimm23-b029","title":"Abstract B029: Investigating therapeutic strategies to promote immune rejection of KRAS G12C inhibitor-resistant sub-populations in lung cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"KRAS; Immune system; Cancer research; Cancer; Lung cancer; Tumor microenvironment; Immunotherapy; Population; Immunology; Cancer cell; Biology; Medicine; Oncology; Colorectal cancer; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002579476,0.0003164173,0.0003568386,0.0002389795,0.0001353627,0.0003583316,0.0003349909,0.0003767076,0.002036799],"category_scores_gemma":[0.00009453011,0.0001151045,0.0002564816,0.000111662,0.0001825547,0.0002127897,0.0002011305,0.0007739972,0.000489071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002565645,"about_ca_system_score_gemma":0.0002982566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004978286,"about_ca_topic_score_gemma":0.0007709567,"domain_scores_codex":[0.9998803,0.00002255899,0.000006584429,0.00002153128,0.00002966512,0.00003938664],"domain_scores_gemma":[0.999944,0.000007086907,0.00001114428,0.000004719462,0.000008173653,0.00002496591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000719448,0.0006107445,0.0003337552,0.0001590998,0.00002021778,0.00005351748,0.00002402254,0.0005223003,0.9834965,0.0002753989,0.0003339095,0.0134511],"study_design_scores_gemma":[0.000551251,0.01966859,0.005730877,0.00002811496,0.0001095083,0.0004729985,0.00007398453,0.004609403,0.9579034,0.000199417,0.01063812,0.00001450469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884555,0.004211987,0.003748587,0.0004317968,0.00008460917,0.0002725842,0.0002923693,0.0001283062,0.002374188],"genre_scores_gemma":[0.9925953,0.001775307,0.002595192,0.000180956,0.00003096826,0.0001672424,0.0002571001,0.0000217922,0.002376224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002036799,"threshold_uncertainty_score":0.006813824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1640714277306277,"score_gpt":0.467417551572898,"score_spread":0.3033461238422704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}