{"id":"W4389241748","doi":"10.1158/2326-6074.tumimm23-a044","title":"Abstract A044: Screening and characterization of CD38 chimeric antigen receptors for the development of natural killer cell-based therapies","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CD38; Jurkat cells; Epitope; Monoclonal antibody; Antigen; Chimeric antigen receptor; Biology; Molecular biology; T cell; Antibody; Chemistry; Immunology; Immune system; Cell biology; CD34; Stem cell","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700602,0.000432278,0.0002110122,0.000350931,0.0001340748,0.0003107903,0.0004549278,0.0003473743,0.002873185],"category_scores_gemma":[0.0002171849,0.0001409922,0.0003339289,0.0002481241,0.0001224358,0.0001700103,0.0002072662,0.0004468865,0.001018745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000323845,"about_ca_system_score_gemma":0.0002383158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004786847,"about_ca_topic_score_gemma":0.000376232,"domain_scores_codex":[0.9997807,0.00003509088,0.00001705063,0.00003166362,0.00008330074,0.00005223716],"domain_scores_gemma":[0.9998946,0.00001770127,0.00001933982,0.00001437457,0.00003131875,0.00002258282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007459863,0.00006520795,0.0001809257,0.00002279258,0.000004489897,0.00003616602,0.000007637522,0.0001751778,0.9976205,0.00005336715,0.0000663616,0.001692714],"study_design_scores_gemma":[0.00003143074,0.000617828,0.00135859,0.000005327669,0.00001996574,0.000264152,0.00001519678,0.001416945,0.9926878,0.00003564441,0.003542701,0.000004380619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858032,0.000868305,0.009912114,0.0001224888,0.00001884766,0.0002314168,0.0008449226,0.0001069604,0.002091788],"genre_scores_gemma":[0.9691422,0.0008442731,0.01938322,0.00008771062,0.00001213116,0.0001913479,0.003698269,0.00004973429,0.006590973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002873185,"threshold_uncertainty_score":0.009611726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05818398266081853,"score_gpt":0.3394267734488005,"score_spread":0.2812427907879819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}