{"id":"W4389241775","doi":"10.1158/2326-6074.tumimm23-a054","title":"Abstract A054: Anti-CTLA-4 generates memory T-cell with greater expansion and functionality than anti-PD-1","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cytotoxic T cell; Memory T cell; Immunotherapy; Cancer immunotherapy; CD8; Immunology; Immune system; T cell; CTLA-4; Cancer research; Cancer; Antigen; Medicine; Biology; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001987631,0.0003154844,0.0002229134,0.0003816394,0.0001425336,0.0003186135,0.0002884318,0.0004027963,0.008613748],"category_scores_gemma":[0.0001279195,0.0001213023,0.0003027343,0.00013452,0.0002077276,0.0002199781,0.0001628965,0.000697211,0.001011563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003015027,"about_ca_system_score_gemma":0.0002369739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003354973,"about_ca_topic_score_gemma":0.0002877061,"domain_scores_codex":[0.9998629,0.00002111273,0.00001183087,0.00002737454,0.00003997645,0.00003691034],"domain_scores_gemma":[0.9999024,0.00002216543,0.00002199359,0.00001046619,0.00001605736,0.00002683371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000751155,0.0001641989,0.0002967133,0.00007799844,0.00001227956,0.00007476184,0.000008508883,0.0001000191,0.9914789,0.0001958365,0.0007638456,0.006075852],"study_design_scores_gemma":[0.0001390762,0.001578773,0.002244435,0.000008478703,0.00003643438,0.0003871781,0.00001191198,0.0005821607,0.9895651,0.0001014435,0.005340622,0.00000430043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837445,0.00229189,0.004684431,0.0005132094,0.0004586091,0.00006802899,0.000877051,0.0003817426,0.006980503],"genre_scores_gemma":[0.9699392,0.0007428306,0.003491899,0.0003049135,0.0001168872,0.00008195107,0.00128612,0.00006176241,0.02397449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008613748,"threshold_uncertainty_score":0.02881581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08523785618377776,"score_gpt":0.3647702423803929,"score_spread":0.2795323861966151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}