{"id":"W4389243215","doi":"10.1182/blood-2023-182130","title":"Long-Term Efficacy and Safety of Elranatamab Monotherapy in the Phase 2 Magnetismm-3 Trial in Relapsed or Refractory Multiple Myeloma (RRMM)","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Internal medicine; Multiple myeloma; Adverse effect; Clinical endpoint; Pomalidomide; Minimal residual disease; Gastroenterology; Phases of clinical research; Lenalidomide; Oncology; Clinical trial; Surgery; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002939949,0.0009946314,0.001963016,0.0002929365,0.0003986263,0.0009723461,0.0006864498,0.001024529,0.002484487],"category_scores_gemma":[0.001169482,0.0003539587,0.001366117,0.000288094,0.0005453627,0.0008777785,0.0003936462,0.002451692,0.0006044835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007711488,"about_ca_system_score_gemma":0.0009429879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004223609,"about_ca_topic_score_gemma":0.001613014,"domain_scores_codex":[0.999162,0.0005158794,0.00003826157,0.00009909362,0.0000560013,0.0001289118],"domain_scores_gemma":[0.9993886,0.0001172588,0.0001971757,0.00004927667,0.00003941239,0.000208288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.837869,0.01781008,0.009542481,0.0008941445,0.002142686,0.0002854322,0.0002109991,0.002538482,0.02509034,0.0002996725,0.005062312,0.09825439],"study_design_scores_gemma":[0.7003435,0.2560035,0.02885118,0.0000893601,0.00149223,0.0005169455,0.00006227854,0.002578662,0.004249171,0.0004874875,0.005265324,0.00006034229],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882261,0.006408833,0.0004151677,0.0006211624,0.0001302751,0.0009398623,0.00124164,0.0001037228,0.001913163],"genre_scores_gemma":[0.991118,0.001480846,0.0009307033,0.0009244919,0.0002161032,0.001742163,0.001979634,0.00002903014,0.00157908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002939949,"threshold_uncertainty_score":0.01554817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04387892977143066,"score_gpt":0.3515561858806986,"score_spread":0.3076772561092679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}