{"id":"W4389243318","doi":"10.1182/blood-2023-189707","title":"Positive Impacts of the Universal Newborn Screening Program on the Outcome of Children with Sickle Cell Disease in the Province of Quebec: A Retrospective Cohort Study","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Medicine; Pediatrics; Retrospective cohort study; Cohort; Referral; Newborn screening; Disease; Acute chest syndrome; Internal medicine; Sickle cell anemia; Family medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001283665,0.0005403053,0.000551033,0.001123689,0.001984366,0.001356223,0.001580001,0.0007725717,0.001994253],"category_scores_gemma":[0.003195892,0.0003783198,0.0009284101,0.002545757,0.0007309748,0.0005635768,0.0008848824,0.0009412415,0.0002167655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01602178,"about_ca_system_score_gemma":0.01375439,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.929207,"about_ca_topic_score_gemma":0.9441877,"domain_scores_codex":[0.9983997,0.0001836355,0.0001330256,0.0003478923,0.0003506429,0.0005850569],"domain_scores_gemma":[0.9958861,0.0003352798,0.001485549,0.0002269463,0.00121978,0.0008462028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00005499654,0.00002647661,0.9988902,0.00001559509,0.0000448902,0.00004476324,0.0001204216,0.00003122505,0.00003856033,0.00001638093,0.000251485,0.0004649629],"study_design_scores_gemma":[0.000009624454,0.00009151705,0.9985737,0.00003944671,0.00004701608,0.0000748522,0.0005312652,0.0002078724,0.00002427665,0.000008511885,0.0003834803,0.000008431713],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935591,0.0005691437,0.00009178381,0.0001513281,0.00001552284,0.0001164139,0.004567706,0.000006823763,0.0009223558],"genre_scores_gemma":[0.9977509,0.0002228669,0.0001058772,0.0001111476,0.0000100723,0.00006469143,0.001436913,0.000003718505,0.0002938067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07079297,"threshold_uncertainty_score":0.1424197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005850833180518811,"score_gpt":0.2333750758106233,"score_spread":0.2275242426301045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}