{"id":"W4389243607","doi":"10.1182/blood-2023-179047","title":"The Role of Gpibα in Control of Megakaryocyte Reactivity to Thrombopoietin","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Thrombopoietin; Megakaryocyte; Platelet; Thrombopoiesis; Haematopoiesis; Internal medicine; Endocrinology; Bone marrow; Chemistry; Immunology; Wild type; Biology; Cell biology; Medicine; Stem cell; Mutant; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707926,0.0004209499,0.000192608,0.0002559903,0.000125518,0.000385167,0.0001700432,0.0003147751,0.0004816708],"category_scores_gemma":[0.0001531639,0.0001715066,0.0001733022,0.000104315,0.0002178846,0.000194348,0.0002239737,0.0004169587,0.0001985485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001939483,"about_ca_system_score_gemma":0.00008521403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002177623,"about_ca_topic_score_gemma":0.0001306859,"domain_scores_codex":[0.9998537,0.00004351646,0.00001201858,0.00002814636,0.00002943118,0.00003313792],"domain_scores_gemma":[0.9998804,0.00001353965,0.00004335623,0.00001053196,0.00001072868,0.00004134355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009975593,0.000005787981,0.0004309349,0.00002305243,0.000004455483,0.0001227067,0.00001325622,0.00003115554,0.9979991,0.000186361,0.00001588511,0.00106758],"study_design_scores_gemma":[0.00009438803,0.0008010807,0.07751639,0.00003951012,0.00006285698,0.001863144,0.0001160613,0.003226151,0.9078188,0.0007926344,0.007649325,0.00001959278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822304,0.01022561,0.005198109,0.0002087195,0.00003723101,0.00003821627,0.0001948063,0.00006516062,0.001801849],"genre_scores_gemma":[0.9935424,0.003761912,0.001535475,0.00004739457,0.0000241615,0.00002243189,0.000140123,0.00001169132,0.0009143077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004816708,"threshold_uncertainty_score":0.001611352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008019635338295797,"score_gpt":0.2507804829246758,"score_spread":0.2427608475863799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}