{"id":"W4389243727","doi":"10.1182/blood-2023-187498","title":"Lintuzumab-Ac225, a CD33-Directed Antibody Radiotherapy, Targets AML in a Mutation Agnostic Manner","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"CD33; Cancer research; Myeloid leukemia; Venetoclax; Leukemia; Medicine; Myeloid; Immunology; Oncology; Biology; Stem cell; CD34; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000975083,0.0002834893,0.0001435335,0.0002070697,0.00009797329,0.0002326731,0.0001997267,0.0002770799,0.001276445],"category_scores_gemma":[0.0000455104,0.00008894495,0.0001374521,0.0001185198,0.0001325006,0.0001162858,0.00009822455,0.000369469,0.0002598153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004516827,"about_ca_system_score_gemma":0.000199784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000659901,"about_ca_topic_score_gemma":0.0008636387,"domain_scores_codex":[0.9999086,0.00001527629,0.000005510095,0.00002361503,0.00002220031,0.0000248726],"domain_scores_gemma":[0.9999789,0.000002596437,0.000007226213,0.000002335828,0.000002328222,0.000006559794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001155816,0.00008464738,0.0003462905,0.0000367469,0.000006844329,0.00003850359,0.000007315793,0.00022879,0.9947,0.0002149964,0.0001266027,0.004093698],"study_design_scores_gemma":[0.00007674161,0.001419556,0.003375462,0.000008024505,0.00002809817,0.0006997235,0.00001203853,0.0020255,0.9854872,0.00006182767,0.006800681,0.000005232132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879436,0.002633394,0.005677339,0.0001546752,0.00003082163,0.0001360706,0.0002909842,0.0001933847,0.002939546],"genre_scores_gemma":[0.9944563,0.0007426495,0.002738334,0.00005370524,0.000007663992,0.00005488348,0.000255653,0.00000510883,0.001685663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276445,"threshold_uncertainty_score":0.004270077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01548342711395424,"score_gpt":0.3191437560677136,"score_spread":0.3036603289537593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}