{"id":"W4389244303","doi":"10.1007/978-1-0716-3589-6_2","title":"N-Terminomics/TAILS of Human Tumor Biopsies and Cancer Cell Lines","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"","keywords":"Proteome; Proteases; Proteolysis; Proteomics; Protease; Stable isotope labeling by amino acids in cell culture; Computational biology; Chemistry; Biology; Biochemistry; Tandem mass spectrometry; Mass spectrometry; Enzyme; Gene; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002425793,0.000288036,0.000149813,0.0002909121,0.000256796,0.0002050941,0.0002018352,0.0002723895,0.001469583],"category_scores_gemma":[0.0002200698,0.0001199028,0.0002172343,0.0002697285,0.0001551063,0.0001422106,0.0001897071,0.0004141222,0.0008215929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001181175,"about_ca_system_score_gemma":0.0002046936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001083013,"about_ca_topic_score_gemma":0.001588738,"domain_scores_codex":[0.9998749,0.00001806035,0.00001170504,0.00003138508,0.00003789599,0.00002605801],"domain_scores_gemma":[0.9998693,0.00003466089,0.00001636322,0.00002182815,0.00004089995,0.00001697344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009171454,0.000009008429,0.0004310095,0.00003261652,0.000005224444,0.00004451135,0.00002266062,0.0000418848,0.9981799,0.00004543517,0.00005295926,0.001043037],"study_design_scores_gemma":[0.00001277489,0.0001757259,0.01640429,0.00001589251,0.00004312146,0.0006012815,0.00008664701,0.001150182,0.9726661,0.00008975843,0.008749006,0.000005277971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.949892,0.003580186,0.03291905,0.0002026353,0.00007687501,0.000143197,0.005762702,0.0001569585,0.007266302],"genre_scores_gemma":[0.9141851,0.004735491,0.03635694,0.0004800934,0.00003991033,0.0003510373,0.02990278,0.0001854912,0.01376327],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001469583,"threshold_uncertainty_score":0.004916251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.033630758746491,"score_gpt":0.4346797115414499,"score_spread":0.4010489527949589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}