{"id":"W4389244847","doi":"10.1042/bcj20230176","title":"Skin in the game: pannexin channels in healthy and cancerous skin","year":2023,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Pannexin; Skin cancer; Keratinocyte; Cell biology; Melanoma; Epidermis (zoology); Biology; Carcinogenesis; Cell type; Dermis; Cancer; Human skin; Cancer research; Cancer cell; Cell; Pathology; Cell culture; Gap junction; Medicine; Anatomy; Intracellular; Connexin; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003227327,0.000406878,0.000681211,0.0008214943,0.0003616702,0.001293617,0.0003974771,0.001458458,0.00207136],"category_scores_gemma":[0.0003974333,0.0001570731,0.0003809046,0.000747553,0.0008085665,0.003247113,0.0007261881,0.002406443,0.0009154655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006482846,"about_ca_system_score_gemma":0.000530088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005969486,"about_ca_topic_score_gemma":0.0009882951,"domain_scores_codex":[0.9998277,0.00003431952,0.00001934164,0.00003841152,0.00005339873,0.00002676023],"domain_scores_gemma":[0.9998792,0.00004387235,0.0000162551,0.000003984543,0.00003319789,0.00002346594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003776189,0.00008941491,0.001309202,0.01265729,0.00009980615,0.002023619,0.001222772,0.0008209702,0.04148335,0.04677708,0.09914292,0.7939959],"study_design_scores_gemma":[0.00001066184,0.0001608503,0.001868923,0.00141055,0.00004403575,0.0042688,0.0004220977,0.0001493174,0.002329259,0.01176857,0.9775334,0.00003349792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00151106,0.9906724,0.0006200949,0.002506659,0.0017062,0.000007017435,0.00003012351,0.00002422342,0.002922344],"genre_scores_gemma":[0.01047614,0.977248,0.0006925864,0.003234193,0.002503849,0.00001482378,0.00009420911,0.00001639726,0.005719734],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00207136,"threshold_uncertainty_score":0.006929338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04881514684637375,"score_gpt":0.3578305231082075,"score_spread":0.3090153762618337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}