{"id":"W4389247999","doi":"10.1182/blood-2023-178772","title":"Red Blood Cell Transfusion Independence Status Is an Independent Predictor of Survival: A Post Hoc Time-Dependent Analysis of the Phase 3 Simplify-1, Simplify-2, and Momentum Trials","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Ruxolitinib; Myelofibrosis; Anemia; Internal medicine; Blood transfusion; Post-hoc analysis; International Prognostic Scoring System; Oncology; Bone marrow; Myelodysplastic syndromes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01332793,0.0009726737,0.00249416,0.0003430932,0.0004305289,0.001350905,0.0008304098,0.0007336183,0.002707708],"category_scores_gemma":[0.007024323,0.0002457197,0.004712504,0.0005517513,0.0005206974,0.001156959,0.0008042165,0.002371306,0.0002848637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004946499,"about_ca_system_score_gemma":0.001224602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007099708,"about_ca_topic_score_gemma":0.001189724,"domain_scores_codex":[0.9949887,0.003328951,0.0002117662,0.0006010824,0.0003567535,0.0005127199],"domain_scores_gemma":[0.9875349,0.008446401,0.001463654,0.00114105,0.000455255,0.0009587525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7716339,0.003461476,0.1672091,0.0007556327,0.02343296,0.0002595899,0.0002441485,0.00388106,0.004737605,0.0002878375,0.00441742,0.01967923],"study_design_scores_gemma":[0.06210816,0.1573119,0.6990071,0.0001248078,0.03909357,0.0006407163,0.0004213507,0.03035984,0.003297896,0.0008743277,0.006553084,0.0002072055],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959576,0.001375872,0.0005382575,0.000185471,0.0000943343,0.0002008143,0.0009819566,0.00003363987,0.000632098],"genre_scores_gemma":[0.9943561,0.0003228255,0.0008048639,0.0002405358,0.00016323,0.0005913686,0.002201725,0.00004449232,0.001274838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01332793,"threshold_uncertainty_score":0.07048565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03165387089884725,"score_gpt":0.3116797957853737,"score_spread":0.2800259248865264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}