{"id":"W4389248758","doi":"10.1182/blood-2023-182171","title":"Multiparametric Flow Cytometry Based Quantification of the Marrow Hematopoietic Stem and Progenitor Compartment in Post Allogeneic Stem Cell Transplant Recipients with Poor Graft Function to Evaluate Hematopoietic Stem Cell Quality and Predict Clinical Outcomes: A Pilot Study","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Cytopenia; Stem cell; CD34; Transplantation; Haematopoiesis; Medicine; Hematopoietic stem cell transplantation; Progenitor cell; Cord blood; Bone marrow; Hematopoietic stem cell; Internal medicine; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000654656,0.0004492567,0.0003231967,0.0007834765,0.0002358788,0.000405186,0.0002926102,0.000394648,0.001104365],"category_scores_gemma":[0.0005182961,0.0001497907,0.0002291787,0.0002707976,0.0003126737,0.0002453571,0.0002771045,0.0003571068,0.000239768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001975804,"about_ca_system_score_gemma":0.00009732771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002565679,"about_ca_topic_score_gemma":0.0001829898,"domain_scores_codex":[0.9996775,0.00008462575,0.00002823584,0.00008868212,0.00007101089,0.00004991877],"domain_scores_gemma":[0.9996969,0.00007247316,0.00008002173,0.00004119594,0.00003437205,0.00007517992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01416428,0.006792054,0.4747517,0.000174551,0.0001109234,0.0009855743,0.0005701859,0.000586686,0.4659541,0.0001519185,0.000375935,0.03538211],"study_design_scores_gemma":[0.0003415717,0.03300885,0.877961,0.0000150033,0.0001446652,0.004329048,0.0002590605,0.003827222,0.07887564,0.0001033414,0.00110147,0.00003305318],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990645,0.0001435346,0.0004914973,0.000006845412,0.00000371185,0.00006069186,0.00007694774,0.00001019711,0.0001420808],"genre_scores_gemma":[0.9986242,0.00007909257,0.0007744648,0.00002499087,0.00001740176,0.00007168434,0.0002316226,0.000004324289,0.0001722533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104365,"threshold_uncertainty_score":0.003694415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08605759025065907,"score_gpt":0.3359481983992653,"score_spread":0.2498906081486062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}