{"id":"W4389259511","doi":"10.1182/blood-2023-187210","title":"Loss of Autophagy Activity during Storage of Hematopoietic Stem Cell Grafts Is Associated with Reduced Potency","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Ottawa","funders":"","keywords":"Potency; Cord blood; Haematopoiesis; CD34; Stem cell; Andrology; Progenitor cell; Cryopreservation; Hematopoietic stem cell; Transplantation; Biology; Chemistry; Immunology; Cell biology; Medicine; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003456537,0.0002278357,0.0003844944,0.0003313718,0.0002057446,0.0008022815,0.0001701435,0.0002098355,0.001749519],"category_scores_gemma":[0.0003726661,0.000133631,0.0003428073,0.0003816297,0.0003129337,0.0003076911,0.0003328231,0.0005466986,0.0003624584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002833061,"about_ca_system_score_gemma":0.0002303026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003742586,"about_ca_topic_score_gemma":0.0005524429,"domain_scores_codex":[0.9997039,0.00003579908,0.00005292956,0.00005846801,0.00008969032,0.00005916223],"domain_scores_gemma":[0.9996245,0.00004850066,0.0001560292,0.00004284432,0.00007135033,0.00005675841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007798461,0.00005813519,0.005856767,0.0001153432,0.00002929185,0.0001826062,0.00009276847,0.0000937491,0.9890509,0.00007693308,0.0001108029,0.003552976],"study_design_scores_gemma":[0.000008866338,0.0007237018,0.09174151,0.00002944123,0.00005730385,0.0006483779,0.0001515913,0.0005880354,0.9041924,0.0001119032,0.001730926,0.00001596589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994544,0.002555139,0.001345278,0.00006000009,0.00002880607,0.0000255873,0.0006109105,0.00004337843,0.0007869208],"genre_scores_gemma":[0.9963334,0.0007380833,0.0008284316,0.00005288539,0.000008993435,0.00004369318,0.000962063,0.00002302882,0.001009479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001749519,"threshold_uncertainty_score":0.005852699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01445663944758877,"score_gpt":0.2385461983992115,"score_spread":0.2240895589516228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}