{"id":"W4389259644","doi":"10.1182/blood-2023-181821","title":"Interest of Cytoreductive Therapy before Allogenic Hematopoietic Stem Cell Transplantation in Childhood Myelodysplastic Syndromes: A Retrospective Study on Behalf of the Société Francophone De Greffe De Moelle Et De Thérapie Cellulaire (SFGM-TC)","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Medicine; Busulfan; Hematopoietic stem cell transplantation; Transplantation; Myelodysplastic syndromes; Internal medicine; Umbilical cord; Pediatrics; Retrospective cohort study; Oncology; Surgery; Bone marrow; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006619081,0.0002094615,0.0002999911,0.0009328884,0.0003255091,0.0005944219,0.00024529,0.0003810581,0.001914906],"category_scores_gemma":[0.001770406,0.0002503667,0.0003614076,0.001005933,0.0003189724,0.0003932761,0.0003224614,0.0003853866,0.0002404516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004328994,"about_ca_system_score_gemma":0.0005163362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001887791,"about_ca_topic_score_gemma":0.002005206,"domain_scores_codex":[0.9993225,0.0001345156,0.0001170095,0.000192711,0.000138181,0.00009503118],"domain_scores_gemma":[0.997721,0.0004740611,0.00126004,0.000131854,0.0001597315,0.0002532894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007236227,0.00001593808,0.997977,0.00001213295,0.00002145943,0.0004115905,0.00005814588,0.00001446169,0.000111042,0.00002156355,0.0001101442,0.001174187],"study_design_scores_gemma":[0.00001431736,0.0002134815,0.990716,0.00004187716,0.00006883521,0.006546243,0.0004541537,0.0001277217,0.0001909558,0.00002807288,0.001590089,0.000008267637],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997976,0.001192572,0.00005374862,0.0000423935,0.000009954942,0.000008285326,0.0002580059,0.000001944955,0.0004570299],"genre_scores_gemma":[0.9992028,0.0003469798,0.00003517996,0.00003514133,0.00001787406,0.000007103807,0.0002780451,0.000002176683,0.00007467299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001914906,"threshold_uncertainty_score":0.006406069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01884524136926775,"score_gpt":0.2895026362594403,"score_spread":0.2706573948901725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}