{"id":"W4389285499","doi":"10.1016/j.gim.2023.101039","title":"Severity-adjusted evaluation of liver transplantation on health outcomes in urea cycle disorders","year":2023,"lang":"en","type":"article","venue":"Genetics in Medicine","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health, Pakistan; National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Executive Agency for Health and Consumers; Rare Diseases Clinical Research Network; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Intellectual and Developmental Disabilities Research Center; European Commission","keywords":"Urea cycle; Liver transplantation; Transplantation; Medicine; Urea; Internal medicine; Intensive care medicine; Gastroenterology; Biology; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001968916,0.000640242,0.0007841281,0.0008081167,0.0003481249,0.001006458,0.0005991449,0.0007095207,0.001330886],"category_scores_gemma":[0.003768015,0.0002275696,0.002907262,0.001095587,0.0003114473,0.0009255018,0.0008650565,0.001372582,0.0001367754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006766865,"about_ca_system_score_gemma":0.0007686854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01171432,"about_ca_topic_score_gemma":0.01404866,"domain_scores_codex":[0.9987952,0.0005260813,0.0001245995,0.0001791063,0.0001482152,0.0002268525],"domain_scores_gemma":[0.9972723,0.0005852323,0.001061004,0.0001641582,0.0002535839,0.0006636752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002382373,0.00007505435,0.9934141,0.0000397282,0.001324662,0.00004450896,0.00002665178,0.0003390731,0.0001333538,0.00004961765,0.0001982453,0.001972713],"study_design_scores_gemma":[0.00004515433,0.0003533512,0.9977387,0.000009156186,0.0004863431,0.00004904365,0.0001041108,0.0009323781,0.00005947193,0.0001025278,0.0001073267,0.0000124229],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971187,0.000903452,0.0001658154,0.0001592177,0.00004015788,0.000009638848,0.001036293,0.00001138438,0.0005553573],"genre_scores_gemma":[0.9989876,0.0001436621,0.00005179753,0.00003091881,0.00002815093,0.000004231542,0.0006442337,0.000001813588,0.0001074992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01171432,"threshold_uncertainty_score":0.02329224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03337989443256359,"score_gpt":0.3446927125190501,"score_spread":0.3113128180864866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}