{"id":"W4389286603","doi":"10.1016/j.annonc.2023.10.673","title":"595P Durable efficacy of zenocutuzumab, a HER2 x HER3 bispecific antibody, in advanced NRG1 fusion-positive (NRG1+) non-small cell lung cancer (NSCLC)","year":2023,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lung cancer; Bispecific antibody; Antibody; Cancer research; Oncology; Immunology; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002109064,0.0002409838,0.0006996461,0.0001493986,0.0002113716,0.0004305273,0.0002633912,0.0004276583,0.003376664],"category_scores_gemma":[0.0002067079,0.0001025484,0.0003636256,0.0002004786,0.0002499121,0.000258613,0.0001322611,0.0009764094,0.0006594053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004224298,"about_ca_system_score_gemma":0.0004054078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001722676,"about_ca_topic_score_gemma":0.003109372,"domain_scores_codex":[0.999916,0.00001122647,0.000004522122,0.00001344117,0.00001410018,0.00004081438],"domain_scores_gemma":[0.9999224,0.00001645137,0.000008598837,0.000009242191,0.000006404572,0.00003683149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1438612,0.01076768,0.009311981,0.0005772461,0.0008897145,0.002464727,0.0002032408,0.004614652,0.2645046,0.001565913,0.01517328,0.5460657],"study_design_scores_gemma":[0.1151822,0.4130516,0.1620274,0.0001799284,0.002112519,0.009846209,0.0002552051,0.0159645,0.2088093,0.001740777,0.07070557,0.0001248049],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904563,0.003065614,0.0003624552,0.0005279899,0.0002011893,0.00006435586,0.0005676215,0.0001222237,0.004632299],"genre_scores_gemma":[0.9943948,0.0009684407,0.0002094708,0.0003030909,0.00004894607,0.00002386686,0.001019943,0.00001913403,0.00301239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003376664,"threshold_uncertainty_score":0.01129603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03239261749654995,"score_gpt":0.4176107955570832,"score_spread":0.3852181780605333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}