{"id":"W4389307403","doi":"10.3390/pr11123364","title":"Biochemical and Functional Characterization by Site-Directed Mutagenesis of a Phospholipase A2 from Scorpio maurus Venom","year":2023,"lang":"en","type":"article","venue":"Processes","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Rivière-du-Loup","funders":"","keywords":"Phosphatidylethanolamine; Biochemistry; Mutant; Phosphatidylcholine; Active site; Amino acid; Tyrosine; Chemistry; Phospholipid; PLD2; Enzyme; Phospholipase A2; Phosphatidylserine; Biology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000346465,0.00009151529,0.0001118802,0.00002854048,0.00005905112,0.00001315803,0.00004007411,0.00006430752,0.00002998909],"category_scores_gemma":[0.0001197409,0.00008922797,0.00002157857,0.0001773362,0.00004378988,0.000004561952,0.00004641363,0.00002336324,0.00001196159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003964455,"about_ca_system_score_gemma":0.00003995789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003364197,"about_ca_topic_score_gemma":0.000008542864,"domain_scores_codex":[0.9994642,0.00001058726,0.0001316156,0.0002141499,0.00008116412,0.00009835597],"domain_scores_gemma":[0.9996989,0.00001348346,0.00006917609,0.00007507967,0.0001060964,0.00003725583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008077387,0.00004596879,0.004237136,0.0001144654,0.00003472191,7.806411e-7,0.00009127312,0.000001534813,0.9932259,0.000002549904,0.001403082,0.0007618117],"study_design_scores_gemma":[0.0003304497,0.0001037451,0.03528189,0.00001967097,0.00002412973,0.000002353608,0.00006495756,0.0001356179,0.9523453,0.00002867168,0.01152263,0.0001406089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969614,0.002172009,0.0002331712,0.00009860631,0.00003826549,0.00006932726,0.0003123357,0.00004335072,0.00007156318],"genre_scores_gemma":[0.9961836,0.001286483,0.00007148257,0.00008335275,0.00007159613,0.00002470132,0.001990139,0.0000129445,0.0002756536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04088062,"threshold_uncertainty_score":0.3638611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085477058994343,"score_gpt":0.2155301368090121,"score_spread":0.2046753662190687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}