{"id":"W4389307403","doi":"10.3390/pr11123364","title":"Biochemical and Functional Characterization by Site-Directed Mutagenesis of a Phospholipase A2 from Scorpio maurus Venom","year":2023,"lang":"en","type":"article","venue":"Processes","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Rivière-du-Loup","funders":"","keywords":"Phosphatidylethanolamine; Biochemistry; Mutant; Phosphatidylcholine; Active site; Amino acid; Tyrosine; Chemistry; Phospholipid; PLD2; Enzyme; Phospholipase A2; Phosphatidylserine; Biology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003048367,0.0006546773,0.0002780471,0.0002467186,0.0001788727,0.0003763737,0.0003417795,0.0004041671,0.000435965],"category_scores_gemma":[0.0003249733,0.0002059106,0.0006411285,0.0003241981,0.0002688258,0.0002109923,0.0002439947,0.0006695699,0.0002631154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003477283,"about_ca_system_score_gemma":0.0002580103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001909902,"about_ca_topic_score_gemma":0.001039311,"domain_scores_codex":[0.9997624,0.00005086649,0.00004553516,0.00003523809,0.00008123824,0.00002473511],"domain_scores_gemma":[0.9998049,0.00004254307,0.00006832741,0.00002245971,0.00002565662,0.00003624148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005680892,0.00002666807,0.0001916453,0.00002046317,0.000007813898,0.0001093771,0.00001833403,0.00016968,0.998978,0.00004495345,0.00000788184,0.0003683357],"study_design_scores_gemma":[0.00002768471,0.0002133941,0.005619017,0.000005981687,0.00003602818,0.000588663,0.00004173201,0.002139685,0.9902232,0.00003788453,0.001054891,0.0000117813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957737,0.0003326676,0.003130339,0.00007642466,0.00001500669,0.00004308356,0.0003349709,0.00002200938,0.0002717488],"genre_scores_gemma":[0.9916654,0.0005018702,0.0054906,0.00004110517,0.00001036451,0.0000510157,0.001226118,0.00003003093,0.0009834209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001909902,"threshold_uncertainty_score":0.003797591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085477058994343,"score_gpt":0.2155301368090121,"score_spread":0.2046753662190687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}