{"id":"W4389307833","doi":"10.1152/ajpcell.00327.2023","title":"Not just fibrotic: endothelial-derived TGFβ maintains contractile function and lymphatic muscle phenotype during homeostasis","year":2023,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Cumming School of Medicine, University of Calgary; Mitacs","keywords":"Homeostasis; Phenotype; Lymphatic system; Function (biology); Transforming growth factor; Lymphatic Endothelium; Cell biology; Smooth muscle; Biology; Pathology; Medicine; Endocrinology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002713579,0.0001887551,0.0001919542,0.0002642648,0.0002074255,0.0006465871,0.0001479193,0.0002466186,0.001304696],"category_scores_gemma":[0.0002494015,0.00008322132,0.0001001408,0.000161936,0.0002881748,0.000471695,0.0002471273,0.0006015148,0.0003044252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001452839,"about_ca_system_score_gemma":0.0002722132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002035015,"about_ca_topic_score_gemma":0.0004078339,"domain_scores_codex":[0.9998978,0.00002029154,0.000008548529,0.00001901906,0.00002681964,0.00002747289],"domain_scores_gemma":[0.9998119,0.00002108232,0.00005550596,0.00002399786,0.00003573155,0.00005173132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001285455,0.00002022221,0.001906922,0.0000705295,0.000004572934,0.0002469747,0.00005485818,0.00005170502,0.9908547,0.000686107,0.00008305883,0.005891685],"study_design_scores_gemma":[0.00006032489,0.0006231627,0.06402916,0.00009783202,0.00005327518,0.005041999,0.0004359205,0.001481943,0.9118479,0.002321775,0.01398494,0.0000218077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740506,0.008134055,0.01114668,0.000899714,0.0001336333,0.00002252308,0.0002530671,0.0001607317,0.005198874],"genre_scores_gemma":[0.9924815,0.002500913,0.001856938,0.000214086,0.00006864915,0.00001338668,0.0001300768,0.00002178031,0.002712637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001304696,"threshold_uncertainty_score":0.00436461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359827145994825,"score_gpt":0.2508558439729435,"score_spread":0.2372575725129953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}