{"id":"W4389346648","doi":"10.1016/j.jtct.2023.11.019","title":"Genetic Findings of Potential Donor Origin following Hematopoietic Cell Transplantation: Recommendations on Donor Disclosure and Genetic Testing from the World Marrow Donor Association","year":2023,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services","funders":"","keywords":"Transplantation; Hematopoietic cell; Medicine; Disease; Genetic testing; Hematopoietic stem cell transplantation; Transplantation Chimera; Haematopoiesis; Intensive care medicine; Bioinformatics; Stem cell; Internal medicine; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003742687,0.0003226498,0.0004166308,0.000235827,0.0002992423,0.00008380589,0.000119582,0.0001569206,0.0001351774],"category_scores_gemma":[0.00001269821,0.0002642812,0.0001539095,0.000637728,0.0000610343,0.0001143177,0.000005503977,0.0002563228,0.00003269233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004841276,"about_ca_system_score_gemma":0.00006585139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001403878,"about_ca_topic_score_gemma":0.00009024857,"domain_scores_codex":[0.997767,0.0002234728,0.0006770627,0.0004831053,0.0005042381,0.0003451057],"domain_scores_gemma":[0.9983177,0.001006136,0.0002197234,0.000241621,0.00007581478,0.0001389642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001162748,0.0002798085,0.5993707,0.001337622,0.0004991426,0.0004251039,0.01195761,0.0003939838,0.3744479,0.0001584093,0.0003942651,0.009572715],"study_design_scores_gemma":[0.01110678,0.0004790252,0.8316712,0.001194889,0.001586595,0.0001850917,0.0009182126,0.001579382,0.1494733,0.0004907096,0.0006548361,0.0006599195],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915502,0.0005937098,0.003687493,0.002201467,0.0002931162,0.0009346806,0.0002103654,0.0001213072,0.0004076683],"genre_scores_gemma":[0.9896166,0.005769759,0.002777403,0.0003209494,0.0001280403,0.00006670955,0.0007412561,0.00005818244,0.0005210387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2323006,"threshold_uncertainty_score":0.9999809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02365778249594678,"score_gpt":0.2589533881061433,"score_spread":0.2352956056101965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}