{"id":"W4389365395","doi":"10.7554/elife.81406.sa2","title":"Author response: Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Candida albicans; Transcriptome; Downregulation and upregulation; Biology; Ribosomal protein; Fluconazole; Ribosome; Corpus albicans; Gene; Cell; Antifungal drug; Fight-or-flight response; Cell biology; Computational biology; Gene expression; Antifungal; Genetics; Microbiology; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003125539,0.0006325584,0.0005231517,0.002044607,0.00130804,0.004177042,0.0009393986,0.001704755,0.1201955],"category_scores_gemma":[0.02577483,0.0001709865,0.0002142259,0.001480082,0.0008618609,0.001457573,0.001758195,0.0008280768,0.05730707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006637005,"about_ca_system_score_gemma":0.004048968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001003099,"about_ca_topic_score_gemma":0.002495855,"domain_scores_codex":[0.9957638,0.0007195438,0.0003115261,0.0003834605,0.002571455,0.0002502485],"domain_scores_gemma":[0.9657386,0.00296639,0.001728189,0.001172123,0.02539037,0.003004453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001953357,0.00008348683,0.003492313,0.001980667,0.00003222651,0.001044822,0.0006408961,0.0002012483,0.01024825,0.001657867,0.69099,0.2894329],"study_design_scores_gemma":[0.00002196452,0.00008423356,0.005705589,0.0003376234,0.00001778675,0.001053882,0.0007136358,0.0001164086,0.003256197,0.0008212163,0.9878455,0.00002594419],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.07206772,0.0379322,0.006645108,0.2567761,0.1485291,0.001766264,0.005447787,0.002614168,0.4682216],"genre_scores_gemma":[0.1570655,0.02791947,0.00467115,0.01282902,0.04541118,0.0002034862,0.003119872,0.0007370139,0.7480433],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.1201955,"threshold_uncertainty_score":0.402094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07539237338526536,"score_gpt":0.3710645452993528,"score_spread":0.2956721719140875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}