{"id":"W4389374453","doi":"10.1212/wnl.98.18_supplement.2799","title":"Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies (S20.010)","year":2022,"lang":"en","type":"article","venue":"Neurology","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Georgetown Hospital","funders":"","keywords":"Dementia with Lewy bodies; Bosutinib; Medicine; Neuroscience; Dementia; Psychology; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001229202,0.0004212304,0.0008340084,0.0001921022,0.000260449,0.0008935363,0.0002794615,0.0005814005,0.002451761],"category_scores_gemma":[0.0009550615,0.0001323556,0.0005970928,0.0001956945,0.000294703,0.0004969955,0.0001909548,0.001422784,0.0006046782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008355933,"about_ca_system_score_gemma":0.0007546915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001110428,"about_ca_topic_score_gemma":0.003149997,"domain_scores_codex":[0.9996384,0.0001088445,0.0000250743,0.00004755716,0.00007530856,0.0001048465],"domain_scores_gemma":[0.9997237,0.00005989924,0.00007653349,0.00001818251,0.00004914703,0.0000724993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1042361,0.007145886,0.02191068,0.002154677,0.001579289,0.0007430149,0.0003198105,0.005522144,0.2873395,0.001865047,0.01074241,0.5564413],"study_design_scores_gemma":[0.05447709,0.4057705,0.1496642,0.001485638,0.00445878,0.004542452,0.00060728,0.01160589,0.2743362,0.005553464,0.08726741,0.0002311846],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9561687,0.03167333,0.00121448,0.001862431,0.0001850513,0.0002483156,0.001110807,0.0001147871,0.007422187],"genre_scores_gemma":[0.9923702,0.00324273,0.0007347777,0.0008777498,0.00006587852,0.0001536309,0.0006078717,0.0000165089,0.001930485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002451761,"threshold_uncertainty_score":0.008201897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306662124840054,"score_gpt":0.2550818171326169,"score_spread":0.2420151958842164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}