{"id":"W4389379865","doi":"10.1016/j.jaci.2023.10.030","title":"Reply","year":2023,"lang":"en","type":"letter","venue":"Journal of Allergy and Clinical Immunology","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston Health Sciences Centre","funders":"","keywords":"Medicine; Epinephrine; Pharmacokinetics; Pharmacodynamics; Adverse effect; Allergy; Anesthesia; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.000584323,0.0002050712,0.001068256,0.000289034,0.00005442749,0.00001245869,0.0001711674,0.001404425,0.00005862952],"category_scores_gemma":[0.001287021,0.0001578713,0.0006033884,0.0001261016,0.0003284489,0.00006585508,0.00009462722,0.006292617,0.0002082765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005991888,"about_ca_system_score_gemma":0.000379543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002162691,"about_ca_topic_score_gemma":0.000006617166,"domain_scores_codex":[0.9976305,0.0002085783,0.001394598,0.0002472356,0.0002319108,0.0002871821],"domain_scores_gemma":[0.9970723,0.001187258,0.0009737896,0.0003661164,0.0002969957,0.0001035027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001116769,0.0001596378,0.0001102447,0.00002513191,0.0086302,0.007866672,0.00002345653,3.038355e-7,0.00008110198,0.00004196509,0.9502252,0.0327244],"study_design_scores_gemma":[0.001515381,0.0005641358,0.02230606,0.0002567502,0.0004448179,0.004582586,0.0000648725,0.000001596817,0.000005101735,0.0003524329,0.969784,0.0001222199],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.006085917,0.001195208,0.00001174842,0.9795956,0.006048862,0.00009297396,0.000004343148,0.00004260947,0.006922724],"genre_scores_gemma":[0.0007785443,0.03958426,0.0004226737,0.9086218,0.0157834,0.000003126139,0.00004623609,0.0001110219,0.03464893],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07097381,"threshold_uncertainty_score":0.9998919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06062839162062543,"score_gpt":0.3656700787555492,"score_spread":0.3050416871349238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}