{"id":"W4389393930","doi":"10.1101/2023.12.05.570300","title":"Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Craniofacial Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Mesenchyme; Cell biology; Morphogenesis; Osteoblast; Biology; Wnt signaling pathway; Anatomy; Mesenchymal stem cell; Chemistry; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007434891,0.0002953488,0.0001618066,0.000260879,0.0002086486,0.0003519192,0.0001715143,0.0002579068,0.001472119],"category_scores_gemma":[0.0001201415,0.0002774955,0.0002223716,0.0001326623,0.0002269174,0.0001596132,0.0003566932,0.0005835799,0.0006616287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003053684,"about_ca_system_score_gemma":0.0002420493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001518631,"about_ca_topic_score_gemma":0.002885294,"domain_scores_codex":[0.9998048,0.0000174801,0.00001858636,0.00002698102,0.00007850198,0.00005361377],"domain_scores_gemma":[0.999785,0.00001850517,0.00007768819,0.00002015787,0.00002439944,0.00007415973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003392156,0.000004157451,0.0002139744,0.000008007829,8.599372e-7,0.00003673183,0.000005827865,0.00001315262,0.9993684,0.00005541894,0.00001666379,0.0002428806],"study_design_scores_gemma":[0.00001896118,0.00005399602,0.02994265,0.000008584836,0.00001129234,0.0003296837,0.00008963118,0.001158773,0.9655042,0.00006329092,0.002814469,0.00000444668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941421,0.0008183588,0.002605782,0.00008016077,0.00001940918,0.00002008003,0.0006388754,0.0001019745,0.001573098],"genre_scores_gemma":[0.9937999,0.0003230125,0.0013031,0.00005190214,0.00000510011,0.00002685201,0.000852895,0.00003575295,0.003601448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518631,"threshold_uncertainty_score":0.004924715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671114434818789,"score_gpt":0.2394085876964137,"score_spread":0.2226974433482258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}