{"id":"W4389397143","doi":"10.1101/2023.12.05.570171","title":"ERK3 Is Involved in Regulating Cardiac Fibroblast Function","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Fibroblast; Cardiac function curve; Cardiac fibrosis; Internal medicine; Endocrinology; Haploinsufficiency; Fibrosis; Myofibroblast; Cardiac myocyte; Myocyte; Medicine; Biology; Heart failure; Phenotype; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008787075,0.0004035,0.0001371872,0.0001465534,0.0002443691,0.0002806775,0.0001739392,0.0002168416,0.001732757],"category_scores_gemma":[0.00007186671,0.0001238445,0.0003149678,0.0001009775,0.000134522,0.0001565824,0.000226131,0.0003962729,0.0004709907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002362608,"about_ca_system_score_gemma":0.0001891145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003313427,"about_ca_topic_score_gemma":0.0005357466,"domain_scores_codex":[0.9999275,0.000008108504,0.000005945777,0.00001559325,0.00001833551,0.00002448414],"domain_scores_gemma":[0.9999503,0.000004105041,0.00001920396,0.000003961152,0.00001018839,0.00001234307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000474179,0.00005355485,0.001421816,0.0001657086,0.00002313157,0.000212422,0.00002286648,0.0001914174,0.9924947,0.0004363046,0.0002397821,0.004264036],"study_design_scores_gemma":[0.00008744048,0.0002853519,0.06507859,0.00004385155,0.00008714786,0.001463125,0.0001254075,0.00435917,0.9181172,0.0007245991,0.009606014,0.0000222182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883731,0.003437704,0.003668045,0.0002550174,0.00005452154,0.00002548116,0.0009570891,0.0001069434,0.003122117],"genre_scores_gemma":[0.9945202,0.00114237,0.001066138,0.0000645238,0.00001217356,0.00002081625,0.0006749997,0.00001426778,0.002484445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001732757,"threshold_uncertainty_score":0.005796671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02500489146800225,"score_gpt":0.2377404082310733,"score_spread":0.2127355167630711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}