{"id":"W4389404532","doi":"10.1212/wnl.98.18_supplement.1199","title":"24-Week Results From Phase 3 Study MT-1186-A01 an Open-Label, Multicenter Safety Study of Oral Edaravone in Subjects With Amyotrophic Lateral Sclerosis (P1-13.001)","year":2022,"lang":"en","type":"article","venue":"Neurology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Amyotrophic lateral sclerosis; Edaravone; Medicine; Open label; Physical medicine and rehabilitation; Audiology; Anesthesia; Internal medicine; Adverse effect; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002209338,0.001369902,0.001848599,0.0003717974,0.0006660094,0.0008299968,0.0008670391,0.001727754,0.003516528],"category_scores_gemma":[0.001589763,0.000528102,0.001641308,0.0002997429,0.0006559967,0.0007688771,0.0002798871,0.002383793,0.0009757989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004993418,"about_ca_system_score_gemma":0.000923517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008326906,"about_ca_topic_score_gemma":0.001569668,"domain_scores_codex":[0.9994076,0.0002870361,0.00003979666,0.00009213015,0.00007601482,0.00009744033],"domain_scores_gemma":[0.9986382,0.0002388807,0.0003633101,0.0001217415,0.0001748321,0.0004629344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8245292,0.03924437,0.007548952,0.000588243,0.001746502,0.0003298802,0.0002497739,0.0009418711,0.06752786,0.0001222402,0.003337386,0.05383371],"study_design_scores_gemma":[0.4686924,0.4678515,0.05051171,0.00005085943,0.00112451,0.0004354415,0.00008324182,0.0007821923,0.007199499,0.0001970598,0.002999811,0.00007187798],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916499,0.002169343,0.0008892418,0.0001914447,0.0001059218,0.001720469,0.002020539,0.0001205703,0.001132552],"genre_scores_gemma":[0.9853433,0.001155437,0.001718801,0.0008092201,0.000203968,0.002824677,0.0048943,0.00006105615,0.002989247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003516528,"threshold_uncertainty_score":0.01176393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1022026540615217,"score_gpt":0.3481979157841184,"score_spread":0.2459952617225967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}