{"id":"W4389437448","doi":"10.1007/s10620-023-08197-5","title":"Hydrogen Sulfide Producers Drive a Diarrhea-Like Phenotype and a Methane Producer Drives a Constipation-Like Phenotype in Animal Models","year":2023,"lang":"en","type":"article","venue":"Digestive Diseases and Sciences","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bausch Health; Cedars-Sinai Medical Center; University of California, Los Angeles; National Philanthropic Trust","keywords":"Methanogen; Lachnospiraceae; Diarrhea; Gut flora; Biology; Internal medicine; Microbiology; Firmicutes; Medicine; Biochemistry; 16S ribosomal RNA; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002619997,0.0006303149,0.0003456619,0.0007431896,0.0002307581,0.0003536265,0.0001971335,0.0004247443,0.001385076],"category_scores_gemma":[0.0002392241,0.0002828694,0.0004409305,0.0002971962,0.0004613663,0.0003011453,0.0003755197,0.001005028,0.0002710226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000362345,"about_ca_system_score_gemma":0.0002789055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007803351,"about_ca_topic_score_gemma":0.00193683,"domain_scores_codex":[0.9997531,0.00005550597,0.00002323949,0.00005164079,0.00005309653,0.00006334225],"domain_scores_gemma":[0.999594,0.00003070036,0.0001512393,0.00004037361,0.00002870085,0.0001549971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001519628,0.0003377928,0.00313614,0.0001110485,0.00004073543,0.000264235,0.00003670679,0.00009158568,0.992013,0.0001164319,0.0001901986,0.002142543],"study_design_scores_gemma":[0.0005490766,0.01838766,0.2106791,0.0001366943,0.0003313768,0.003631508,0.000764577,0.003513333,0.7506048,0.0006685162,0.01065607,0.00007728805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955605,0.001247552,0.001545523,0.0002575258,0.0000472437,0.0000436262,0.0004855033,0.00009423753,0.0007183301],"genre_scores_gemma":[0.9923635,0.001939312,0.002129333,0.0001885129,0.0000269764,0.00008263907,0.0007129993,0.00002453457,0.002532148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001385076,"threshold_uncertainty_score":0.004633486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0293556738753483,"score_gpt":0.2867055081649545,"score_spread":0.2573498342896062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}