{"id":"W4389441048","doi":"10.1212/wnl.92.15_supplement.p2.4-028","title":"Prospective, Open-Label Study Evaluating the Safety and Tolerability of Higher Infusion Rates of Intravenous Immunoglobulin in Patients with Chronic Inflammatory Demyelinating Polyneuropathy. Interim analyses. (P2.4-028)","year":2019,"lang":"en","type":"article","venue":"Neurology","topic":"Peripheral Neuropathies and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Chronic inflammatory demyelinating polyneuropathy; Medicine; Tolerability; Interim; Interim analysis; Antibody; Intravenous Immunoglobulins; Adverse effect; Internal medicine; Immunology; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005714998,0.0001945055,0.0006118896,0.0000868356,0.00006153543,0.00001102621,0.0002261375,0.00006814468,0.00006216673],"category_scores_gemma":[0.0001921194,0.0001275456,0.00002692471,0.0002871024,0.0002052675,0.0001009115,0.0004154287,0.0004319517,0.000001355874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004027606,"about_ca_system_score_gemma":0.0001287377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005276725,"about_ca_topic_score_gemma":0.0002889396,"domain_scores_codex":[0.9978324,0.0005621726,0.0006712937,0.0004275401,0.0002541319,0.0002524211],"domain_scores_gemma":[0.9987845,0.0001786189,0.0003727767,0.0004339625,0.0001929927,0.00003711406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01099117,0.001396347,0.9677445,0.0001065039,0.00003989785,0.000008486387,0.001092407,0.0001877434,0.01324229,0.00001442013,7.115815e-7,0.005175512],"study_design_scores_gemma":[0.01267703,0.03478976,0.950772,0.00004830933,0.0000527104,0.000004547729,0.0001064796,0.001286349,0.0001299065,0.00002352723,0.00001576796,0.00009365757],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971873,0.0002129734,0.000002161852,0.0001484125,0.0001341127,0.002088852,0.000004285257,0.00001183132,0.0002100399],"genre_scores_gemma":[0.9995691,0.00002423458,0.00002600437,0.0002994843,0.00001372058,0.00002333716,0.00000371281,0.00002372481,0.00001670427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03339341,"threshold_uncertainty_score":0.5201159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02900308583864808,"score_gpt":0.3420407258415671,"score_spread":0.3130376400029191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}