{"id":"W4389441361","doi":"10.1212/wnl.92.15_supplement.s16.007","title":"The Efficacy and Safety Results of Laquinimod as a Treatment for Huntington Disease (LEGATO-HD) (S16.007)","year":2019,"lang":"en","type":"article","venue":"Neurology","topic":"Adolescent and Pediatric Healthcare","field":"Health Professions","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Huntington's disease; Gerontology; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258192,0.0003720087,0.000574003,0.0003158627,0.0002531064,0.0003611212,0.0002763668,0.0006761302,0.003026911],"category_scores_gemma":[0.00145957,0.00009214587,0.0005633918,0.0001994566,0.0005385884,0.0003469313,0.0001716597,0.0008755536,0.0007788735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004117457,"about_ca_system_score_gemma":0.0004586969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007027113,"about_ca_topic_score_gemma":0.001272453,"domain_scores_codex":[0.9995472,0.0002220874,0.0000396647,0.00005803174,0.00008319857,0.00004979749],"domain_scores_gemma":[0.9990448,0.0003010774,0.000193204,0.00006413159,0.0001533057,0.0002434582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.35912,0.02536829,0.03952867,0.00133611,0.002038756,0.001219456,0.0004003719,0.001311591,0.1746225,0.0007027801,0.007815105,0.3865365],"study_design_scores_gemma":[0.09642616,0.7475231,0.09567592,0.0001860209,0.001437806,0.001912774,0.0001716314,0.001395808,0.04153207,0.0003808044,0.0132951,0.00006280252],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854144,0.005751289,0.0002880249,0.0004312424,0.0001059882,0.000319042,0.001161572,0.00004354979,0.006484906],"genre_scores_gemma":[0.9935024,0.001668324,0.0006850333,0.0005224817,0.0001528528,0.0001045502,0.001556272,0.00001708911,0.001790928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003026911,"threshold_uncertainty_score":0.01012599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04305166481979036,"score_gpt":0.3987612608281023,"score_spread":0.355709596008312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}