{"id":"W4389442055","doi":"10.1161/hypertensionaha.123.21716","title":"Endothelin System in Hypertension and Chronic Kidney Disease","year":2023,"lang":"en","type":"review","venue":"Hypertension","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Medicine; Kidney disease; Endothelin receptor; Internal medicine; Kidney; Disease; Endothelin 1; Endocrinology; Cardiology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002840797,0.0005486785,0.000900369,0.001382593,0.0002707645,0.000741902,0.000452179,0.0006723137,0.00377567],"category_scores_gemma":[0.000451498,0.0001275227,0.0003503911,0.001551,0.0002850493,0.00083684,0.0005218588,0.001273127,0.001287396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004289659,"about_ca_system_score_gemma":0.001133652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009905617,"about_ca_topic_score_gemma":0.001815126,"domain_scores_codex":[0.9998676,0.00002308533,0.00002236651,0.00002068024,0.00005145649,0.00001477161],"domain_scores_gemma":[0.999844,0.0000650728,0.00002768148,0.000004041331,0.00004204983,0.0000171774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008338712,0.00006361714,0.0003096038,0.02013983,0.0001113872,0.0004169686,0.0001095646,0.0003034011,0.001563658,0.003930368,0.05123921,0.9217289],"study_design_scores_gemma":[0.00001695435,0.00009581367,0.001545985,0.005514382,0.0001369314,0.002521351,0.00009039805,0.00007677831,0.0002221923,0.002783029,0.9869792,0.00001695425],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008391215,0.9987984,0.00003814277,0.0001928183,0.0002369743,0.000001800352,0.000008468104,0.000003528799,0.0006359938],"genre_scores_gemma":[0.0007355215,0.9980939,0.0000637671,0.0001916969,0.0002459474,0.000002691624,0.00001945267,6.956615e-7,0.0006462598],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00377567,"threshold_uncertainty_score":0.01263082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0616174331131541,"score_gpt":0.3001290772652546,"score_spread":0.2385116441521005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}