{"id":"W4389446107","doi":"10.1212/wnl.96.15_supplement.4448","title":"Serotonin Receptor Activity Profiles for Nine Commercialized Ergot Alkaloids Correspond to Known Risks of Fibrosis and Hallucinations (4448)","year":2021,"lang":"en","type":"article","venue":"Neurology","topic":"Plant and fungal interactions","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"","keywords":"Serotonin; Receptor; Neuroscience; Medicine; Pharmacology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000858788,0.00008714534,0.0001952194,0.00001805473,0.000146346,0.00001802469,0.00008552376,0.00009748048,0.0004548481],"category_scores_gemma":[0.000205287,0.00004282476,0.00005658056,0.0001851747,0.00004113336,0.00006202086,0.00006854676,0.0001079934,0.000009797329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004399551,"about_ca_system_score_gemma":0.00001004337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003369388,"about_ca_topic_score_gemma":0.002487546,"domain_scores_codex":[0.9992895,0.0001314,0.0001321251,0.0002299729,0.00005797575,0.0001590709],"domain_scores_gemma":[0.9988862,0.0008244959,0.00006381048,0.00004457453,0.0001138888,0.00006709053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007505845,0.0002179763,0.004685514,0.000006873435,0.00001281034,0.000001455611,0.00004688324,0.000003719025,0.9744943,0.0002938345,0.005375848,0.01411014],"study_design_scores_gemma":[0.0005693846,0.002969677,0.5063258,0.00001309247,0.00003492441,0.00003198129,0.00003556872,0.0003848967,0.1769361,0.000150272,0.3123562,0.0001920575],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875408,0.00003781694,0.00002705646,0.01077853,0.0002606445,0.0002905376,0.0006814165,0.00002384995,0.0003593621],"genre_scores_gemma":[0.9978974,0.00003404601,0.0002779455,0.0006398647,0.0001067221,0.00009650543,0.0001242443,0.000001111816,0.0008221698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7975582,"threshold_uncertainty_score":0.4980268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0707369404078975,"score_gpt":0.3119295397013755,"score_spread":0.241192599293478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}