{"id":"W4389446147","doi":"10.1212/wnl.96.15_supplement.4584","title":"Sustained Improvements in Motor and Non-Motor Symptoms in Advanced Parkinson’s Disease Patients Treated with Carbidopa Levodopa Enteral Suspension in a ‘Real-World’ Study: Interim Results of the Multinational DUOGLOBE Study With at Least 24 Months Follow-Up (4584)","year":2021,"lang":"en","type":"article","venue":"Neurology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Selkirk College","funders":"","keywords":"Carbidopa; Levodopa; Enteral administration; Interim; Medicine; Parkinson's disease; Multinational corporation; Interim analysis; Disease; Internal medicine; Clinical trial; Parenteral nutrition; Political science; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003738422,0.0007752363,0.001299629,0.0004304877,0.0005269176,0.001167738,0.0005773679,0.001120923,0.0009257103],"category_scores_gemma":[0.002786675,0.0004701355,0.001859765,0.000762157,0.0006685475,0.001095883,0.0006797823,0.001172605,0.0002753392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006382366,"about_ca_system_score_gemma":0.0004923764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002434797,"about_ca_topic_score_gemma":0.003306031,"domain_scores_codex":[0.9984438,0.000838425,0.0001503494,0.0002265213,0.0001519326,0.0001890971],"domain_scores_gemma":[0.9969082,0.0005228887,0.001159469,0.0003664558,0.0002943963,0.0007486679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1568944,0.004634647,0.8164474,0.0001916125,0.004449435,0.000335704,0.0004633382,0.0003071273,0.003849813,0.00002676707,0.0004276707,0.01197199],"study_design_scores_gemma":[0.004708541,0.02237714,0.9708359,0.00001470399,0.0007381574,0.0002269859,0.0001494882,0.0002122807,0.0003728597,0.00001302977,0.000325356,0.0000256574],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999068,0.0003460271,0.0000509508,0.00002542604,0.000007528578,0.0000456903,0.0002797976,0.00000453055,0.0001720636],"genre_scores_gemma":[0.9982678,0.0001242324,0.0001788073,0.00007434557,0.00002346083,0.00005218309,0.001099762,0.000002726155,0.0001767234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003738422,"threshold_uncertainty_score":0.01977086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008633414138564891,"score_gpt":0.2522557772722162,"score_spread":0.2436223631336513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}