{"id":"W4389447002","doi":"10.1212/wnl.94.15_supplement.2135","title":"Neurofilament Light-Chain Protein as A Potential Biomarker of Neurodegeneration and Progression in Former Contact Sports Athletes (2135)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"Genetics and Physical Performance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto Western Hospital; University of Toronto","funders":"","keywords":"Neurodegeneration; Biomarker; Athletes; Medicine; Neuroscience; Physical medicine and rehabilitation; Pathology; Physical therapy; Psychology; Biology; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005648454,0.0001265308,0.0001493297,0.00002824884,0.00002671125,0.000007995157,0.0000776867,0.0001060619,0.00000828701],"category_scores_gemma":[0.00002657081,0.000113534,0.00003933732,0.00006455491,0.00003761021,0.000004101513,0.00009741676,0.00009715633,0.000001694784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001121161,"about_ca_system_score_gemma":0.00002537127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001164348,"about_ca_topic_score_gemma":0.000008335795,"domain_scores_codex":[0.9990888,0.00006705451,0.0002153576,0.000341888,0.0001081405,0.0001787762],"domain_scores_gemma":[0.9996592,0.000003624785,0.0000945664,0.0001351715,0.00003241251,0.00007504133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005898384,0.00005688342,0.005629155,0.0000246105,0.000005171833,0.00001666622,0.00003568951,0.00007458378,0.9891304,0.00006669707,0.00005746577,0.004312888],"study_design_scores_gemma":[0.0010507,0.005295175,0.08570073,0.00001166404,0.00001125492,0.00001980342,0.000003277207,0.004504324,0.8970848,0.0001142664,0.006023251,0.000180699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970446,0.0002517255,0.00008087765,0.002044876,0.00006628843,0.0003628528,0.000003480487,0.000005274885,0.0001400237],"genre_scores_gemma":[0.9983259,0.00008399496,0.00007558647,0.001349281,0.00008730428,0.00002855119,0.00002435243,0.00001531092,0.000009648482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09204549,"threshold_uncertainty_score":0.4629784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007072581024953184,"score_gpt":0.2272977106565112,"score_spread":0.220225129631558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}