{"id":"W4389449792","doi":"10.1212/wnl.94.15_supplement.4239","title":"Metabolic Stress Induces the Mislocalization of RNA Binding Protein TDP-43 in Human Oligodendrocytes in Vitro (4239)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"In vitro; RNA; RNA-binding protein; Cell biology; Chemistry; Molecular biology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433971,0.0001769566,0.0001471446,0.0001389152,0.0001721047,0.0002025746,0.00007996819,0.0001700653,0.001275008],"category_scores_gemma":[0.00008349206,0.0001267635,0.0002387326,0.0001559361,0.0001147927,0.000121946,0.0001370913,0.0002385993,0.0003743648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052111,"about_ca_system_score_gemma":0.0001515165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002080116,"about_ca_topic_score_gemma":0.002653385,"domain_scores_codex":[0.999923,0.00001647763,0.00001148978,0.00001726604,0.00001464028,0.00001716569],"domain_scores_gemma":[0.9999573,0.000009500012,0.000008665084,0.000007926959,0.000007148167,0.000009393964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002624353,0.00002513105,0.0009202134,0.00002876786,0.000008673089,0.0001632862,0.00005306571,0.00003452011,0.9976732,0.00004657752,0.0000459016,0.0007381915],"study_design_scores_gemma":[0.00001222326,0.000437145,0.02063589,0.000003795935,0.00002130128,0.0005501915,0.0001133846,0.0003343277,0.9758826,0.00004231852,0.001963015,0.000003790553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979458,0.0005458095,0.0005706878,0.00004667287,0.00001889755,0.000008560341,0.0002427105,0.000013957,0.0006068851],"genre_scores_gemma":[0.9960223,0.0005130178,0.0008493416,0.00004321671,0.000007195555,0.00002526657,0.0007860612,0.000009586451,0.001744038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002080116,"threshold_uncertainty_score":0.004265308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0189346851480965,"score_gpt":0.2708761339167815,"score_spread":0.251941448768685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}