{"id":"W4389451993","doi":"10.1101/2023.12.06.570086","title":"Superoxide Dismutases maintain niche homeostasis in stem cell populations","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Science and Engineering Research Board; University of Toronto; York University","keywords":"Niche; Lineage (genetic); Homeostasis; Stem cell; Biology; Evolutionary biology; Redox; Cell biology; Computational biology; Ecology; Genetics; Chemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001788703,0.0002041677,0.0001933256,0.000318454,0.0001551918,0.0003999347,0.0001752238,0.0002406672,0.0009037597],"category_scores_gemma":[0.000145111,0.000112822,0.0001182,0.0001354165,0.0002369245,0.0002249579,0.0003479643,0.0003359043,0.0003841567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001850088,"about_ca_system_score_gemma":0.0001444534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002161987,"about_ca_topic_score_gemma":0.0002710378,"domain_scores_codex":[0.9998928,0.00001201315,0.000008082868,0.00003097638,0.00003122901,0.00002486775],"domain_scores_gemma":[0.9998252,0.00002179228,0.00004604577,0.00002593654,0.00003006322,0.0000510759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005175198,0.000007845921,0.0007697133,0.00001428586,0.000002657215,0.00002904277,0.00001644035,0.0000324464,0.9976684,0.0002110143,0.0000343366,0.001162041],"study_design_scores_gemma":[0.00001600242,0.0001014949,0.01322778,0.000005584863,0.00001273151,0.0002910139,0.00006093051,0.001502747,0.980041,0.0006836162,0.004052883,0.000004288533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919877,0.001329736,0.005035862,0.00008110183,0.00002811931,0.00001157993,0.0002353928,0.0001069869,0.001183489],"genre_scores_gemma":[0.9953799,0.0002145271,0.001560821,0.00001920689,0.00001141034,0.000009742148,0.0003619494,0.00002247524,0.002420089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009037597,"threshold_uncertainty_score":0.003023386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02651290241894778,"score_gpt":0.2527655613638888,"score_spread":0.226252658944941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}