{"id":"W4389452403","doi":"10.1002/advs.202302903","title":"Microfluidic‐Based Reconstitution of Functional Lymphatic Microvasculature: Elucidating the Role of Lymphatics in Health and Disease","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; Leverhulme Trust; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Emergent Behaviors of Integrated Cellular Systems; National Cancer Institute; National Science Foundation","keywords":"Lymphatic system; Lymphangiogenesis; Lymphatic Endothelium; Interstitial fluid; In vivo; Immune system; Lymphatic vessel; Organ-on-a-chip; Inflammation; Pathology; Biology; Cell biology; Medicine; Immunology; Cancer; Nanotechnology; Materials science; Microfluidics; Metastasis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002177189,0.0001871759,0.0001810871,0.0001711335,0.0001153988,0.0003106653,0.0002325764,0.0002202774,0.0005567162],"category_scores_gemma":[0.0001785084,0.0001074405,0.0001952727,0.00009494323,0.0002502803,0.0002337747,0.0003021187,0.000313519,0.00009647299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00027782,"about_ca_system_score_gemma":0.0003038713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003207808,"about_ca_topic_score_gemma":0.0003090591,"domain_scores_codex":[0.9999138,0.00001367551,0.00000490118,0.00001822427,0.00001845793,0.00003091817],"domain_scores_gemma":[0.9999332,0.00001647714,0.00002025556,0.000009338795,0.000006841577,0.00001384754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000598539,0.00005748742,0.0002673397,0.0000769354,0.00000689904,0.00004064675,0.00002125236,0.001818034,0.9908603,0.00181961,0.0001558738,0.004815702],"study_design_scores_gemma":[0.000033184,0.0002533946,0.00151208,0.00001690199,0.00001651346,0.00009295739,0.00002538431,0.02723463,0.964111,0.0004373696,0.006254029,0.00001245856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9412699,0.001955396,0.05302358,0.0002749352,0.0001566278,0.00007880234,0.0003236439,0.000285777,0.002631289],"genre_scores_gemma":[0.9850128,0.0008830872,0.01301007,0.00006756187,0.0000164744,0.00006810624,0.0001554021,0.00001953397,0.0007671166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005567162,"threshold_uncertainty_score":0.00201571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504364431269133,"score_gpt":0.2774206303872985,"score_spread":0.2623769860746071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}