{"id":"W4389452403","doi":"10.1002/advs.202302903","title":"Microfluidic‐Based Reconstitution of Functional Lymphatic Microvasculature: Elucidating the Role of Lymphatics in Health and Disease","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; Leverhulme Trust; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Emergent Behaviors of Integrated Cellular Systems; National Cancer Institute; National Science Foundation","keywords":"Lymphatic system; Lymphangiogenesis; Lymphatic Endothelium; Interstitial fluid; In vivo; Immune system; Lymphatic vessel; Organ-on-a-chip; Inflammation; Pathology; Biology; Cell biology; Medicine; Immunology; Cancer; Nanotechnology; Materials science; Microfluidics; Metastasis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006870062,0.00007937964,0.0001961372,0.0001985896,0.0001242414,0.000008523146,0.00009166819,0.00001556769,0.000005410114],"category_scores_gemma":[0.001289626,0.00005611351,0.00004485571,0.001154704,0.0006292841,0.0001482238,0.00003604065,0.00001028888,0.000002331331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009491849,"about_ca_system_score_gemma":0.002197589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003854019,"about_ca_topic_score_gemma":0.000002012121,"domain_scores_codex":[0.9988062,0.00004351873,0.0003551963,0.0002195563,0.0003762305,0.0001993253],"domain_scores_gemma":[0.9990494,0.0001981399,0.0001713998,0.0002583294,0.0001089933,0.0002137293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004735717,0.00032196,0.4500595,0.00191924,0.00002691798,0.00001210019,0.001244362,0.002178744,0.4708616,0.006243451,0.0001626604,0.06649588],"study_design_scores_gemma":[0.007826643,0.0003528911,0.8064705,0.004313247,0.0001130126,0.00006034526,0.007815612,0.04293745,0.122219,0.006714416,0.0008052991,0.0003715852],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822898,0.01554665,0.0008506362,0.0005836981,0.0001272668,0.0004326801,0.0000127386,0.00002649006,0.0001300663],"genre_scores_gemma":[0.998726,0.000321202,0.0005787867,0.0003041733,0.00001469141,0.00001583227,0.00001324389,0.000004624779,0.00002150219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.356411,"threshold_uncertainty_score":0.389843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504364431269133,"score_gpt":0.2774206303872985,"score_spread":0.2623769860746071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}