{"id":"W4389453236","doi":"10.30683/1929-2279.2023.12.8","title":"Understanding the Warburg Effect Yields New Insights into the Metabolic Control of Cancer","year":2023,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto","keywords":"Warburg effect; Cancer cell; Cancer; Biology; Anaerobic glycolysis; Anaerobic exercise; Cellular respiration; Metabolic pathway; Metabolism; Biochemistry; Physiology; Mitochondrion; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004425932,0.000407699,0.0005059058,0.000521719,0.0005167028,0.001259015,0.0006070513,0.001290017,0.007064655],"category_scores_gemma":[0.0007113672,0.000231897,0.0005959612,0.000354896,0.001391439,0.002292341,0.001011465,0.002282516,0.001264644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001164814,"about_ca_system_score_gemma":0.0006999256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00111877,"about_ca_topic_score_gemma":0.001181164,"domain_scores_codex":[0.9997999,0.00004283214,0.000009456813,0.0000489839,0.00005917982,0.00003959437],"domain_scores_gemma":[0.9997355,0.00009104864,0.00005929102,0.00002813844,0.00005212015,0.00003386222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002657189,0.0001048976,0.002051592,0.001503372,0.0001138301,0.001163824,0.0004045953,0.004541588,0.1187224,0.5914029,0.02842819,0.251297],"study_design_scores_gemma":[0.00004364033,0.0003797884,0.003212909,0.0002356396,0.00007556441,0.001848005,0.000341045,0.005867814,0.07964787,0.2891328,0.6191314,0.00008340496],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.07034574,0.464337,0.1637672,0.09729254,0.01429851,0.0001948817,0.001012644,0.001004443,0.1877471],"genre_scores_gemma":[0.544924,0.3275768,0.04106488,0.01436524,0.006274172,0.000215165,0.0004879026,0.0001753795,0.06491641],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007064655,"threshold_uncertainty_score":0.0236336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2913231829374976,"score_gpt":0.536669185418853,"score_spread":0.2453460024813554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}