{"id":"W4389466199","doi":"10.1212/wnl.90.15_supplement.p1.367","title":"Efficacy of Delayed-Release Dimethyl Fumarate in Newly Diagnosed and Other Early Multiple Sclerosis Patients, and Patients Switching from Interferon or Glatiramer Acetate, in Routine Medical Practice: Interim Results from ESTEEM (P1.367)","year":2018,"lang":"en","type":"article","venue":"Neurology","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cambridge Memorial Hospital","funders":"","keywords":"Glatiramer acetate; Interim; Dimethyl fumarate; Multiple sclerosis; Medicine; Relapsing remitting; Medical practice; Psychiatry; Family medicine; History","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001696406,0.0004040953,0.000964062,0.0003526993,0.0002666563,0.0005248486,0.0004010666,0.0006983698,0.001540607],"category_scores_gemma":[0.002485107,0.0002259929,0.001151207,0.0002513823,0.0003207649,0.0006492067,0.0002949833,0.001011712,0.000229229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004439483,"about_ca_system_score_gemma":0.0004965289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001149514,"about_ca_topic_score_gemma":0.002515565,"domain_scores_codex":[0.9993851,0.000301099,0.00005495708,0.0001217561,0.00006504411,0.00007202956],"domain_scores_gemma":[0.9983385,0.0005571601,0.000509009,0.00008717806,0.0001127155,0.0003954892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6873879,0.01356021,0.1966524,0.0006072157,0.002338713,0.0001675053,0.000371231,0.0005017465,0.006537935,0.00007618781,0.0008639367,0.09093505],"study_design_scores_gemma":[0.1298969,0.3393809,0.5204223,0.0001673914,0.002985649,0.0003792221,0.0003675855,0.001463659,0.003058777,0.0001986289,0.001611994,0.00006710381],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976919,0.001515812,0.00004311697,0.00007640424,0.00001583082,0.00006394683,0.0002123753,0.000006546376,0.0003741981],"genre_scores_gemma":[0.9984792,0.0004388496,0.0001981914,0.0001226211,0.00004158856,0.00005641535,0.0003792574,0.000002361357,0.0002815742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001696406,"threshold_uncertainty_score":0.008971572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03447999574679048,"score_gpt":0.306230744257651,"score_spread":0.2717507485108606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}