{"id":"W4389485543","doi":"10.20944/preprints202312.0351.v1","title":"Thirty Risk Factors for Alzheimer’s Disease Unified by a 
Common Neuroimmune-Neuroinflammation Mechanism","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Neuroinflammation; Mechanism (biology); Neuroscience; Disease; Microglia; Mirroring; Pathogenesis; Psychology; Medicine; Bioinformatics; Immunology; Biology; Inflammation; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001620523,0.000847324,0.0015697,0.006354755,0.0004311158,0.001259045,0.0004636541,0.0006871527,0.003715854],"category_scores_gemma":[0.003511652,0.0002738652,0.002825512,0.006080671,0.0005035453,0.0009823757,0.001160187,0.000640285,0.0008121592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009964567,"about_ca_system_score_gemma":0.00307341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004842959,"about_ca_topic_score_gemma":0.00634155,"domain_scores_codex":[0.9990844,0.0001795519,0.0003000477,0.0001460085,0.0002403055,0.00004974572],"domain_scores_gemma":[0.9980668,0.001012561,0.000552896,0.0000509644,0.0002257027,0.0000910333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001212246,0.00008761374,0.08895562,0.1265393,0.00647646,0.0009795533,0.001747459,0.0004691364,0.001336409,0.009000874,0.02202699,0.7411683],"study_design_scores_gemma":[0.0004058418,0.0007038179,0.4165356,0.1256394,0.03707481,0.009987494,0.002055556,0.0007211691,0.001823717,0.01637418,0.3883802,0.0002983007],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02362737,0.9634596,0.001501611,0.001457257,0.0003810727,0.0002495332,0.004958223,0.00009399901,0.004271313],"genre_scores_gemma":[0.1304024,0.8504968,0.0081009,0.001166642,0.0003876071,0.0006337874,0.006759863,0.00004087243,0.002011132],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006354755,"threshold_uncertainty_score":0.01243073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2247912125101093,"score_gpt":0.3550532966468014,"score_spread":0.1302620841366921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}