{"id":"W4389506989","doi":"10.1038/s42003-023-05589-1","title":"Activation of the glutamatergic cingulate cortical-cortical connection facilitates pain in adult mice","year":2023,"lang":"en","type":"article","venue":"Communications Biology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Fundamental Research Funds for the Central Universities; Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Neuroscience; Excitatory postsynaptic potential; Anterior cingulate cortex; Glutamatergic; Inhibitory postsynaptic potential; Glutamate receptor; Psychology; Medicine; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007577935,0.00008156103,0.0001299077,0.0001871948,0.000359004,0.00001117806,0.001028325,0.00007449734,0.0000266378],"category_scores_gemma":[0.006322178,0.00006096621,0.0000407068,0.001386385,0.001130291,0.00008221048,0.000414255,0.0004500477,0.00007269905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002693119,"about_ca_system_score_gemma":0.00005905881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000367047,"about_ca_topic_score_gemma":0.00001748517,"domain_scores_codex":[0.9963458,0.002698665,0.0003064827,0.0002674877,0.00009994015,0.0002816439],"domain_scores_gemma":[0.9956234,0.003439816,0.00008145239,0.0007420745,0.00006826603,0.00004505496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000262632,0.00007281711,0.006972294,0.000006776632,0.000001054494,8.75121e-7,0.000149264,0.00003463381,0.9875459,0.004420682,0.00005530228,0.000714139],"study_design_scores_gemma":[0.0003341413,0.0001866679,0.03635349,0.0000164938,0.000004027383,0.0000076821,0.0001385899,0.02355256,0.9366596,0.00188694,0.0007715667,0.00008825619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933754,0.000006969981,0.00002790278,0.005886192,0.0001411576,0.0002792887,0.00001388561,0.00006562236,0.0002035884],"genre_scores_gemma":[0.9984782,0.0003108512,0.00001360662,0.00102898,0.000006512105,0.00005779287,0.000004213427,0.000006897477,0.00009299678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05088631,"threshold_uncertainty_score":0.7568694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09964252168638979,"score_gpt":0.3836921273656274,"score_spread":0.2840496056792375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}