{"id":"W4389527316","doi":"10.21203/rs.3.rs-3459629/v1","title":"High circulating MIF levels indicate the association with atypical antipsychotic-induced metabolic adverse effects","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; China Scholarship Council; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Antipsychotic; Medicine; Adverse effect; Internal medicine; Macrophage migration inhibitory factor; Insulin resistance; Endocrinology; Schizophrenia (object-oriented programming); Diabetes mellitus; Pharmacology; Psychiatry; Cytokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000226909,0.0004195961,0.0003270444,0.0006628598,0.0002655658,0.0004730578,0.0001538406,0.000486986,0.003833676],"category_scores_gemma":[0.001481359,0.0001401782,0.000240069,0.0005253401,0.0002599152,0.000155933,0.0002242797,0.0006828571,0.0002045892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002348741,"about_ca_system_score_gemma":0.0002761005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001289096,"about_ca_topic_score_gemma":0.001211246,"domain_scores_codex":[0.9998519,0.00003727087,0.00001664918,0.00002443857,0.00003926252,0.00003047515],"domain_scores_gemma":[0.998546,0.0002764121,0.0008975564,0.00006714419,0.00006687885,0.0001460853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004154434,0.0001072391,0.9489918,0.0001471734,0.0002136628,0.002848814,0.0001193358,0.0001031805,0.02788646,0.0002424477,0.0006149553,0.01457051],"study_design_scores_gemma":[0.00002059388,0.0002611714,0.9934698,0.0000181539,0.00007002569,0.003043266,0.00009560503,0.0002225577,0.002093361,0.0002409826,0.0004561495,0.000008238128],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951199,0.001922958,0.0004604143,0.0002608797,0.00004231094,0.00001272379,0.000666017,0.00002492513,0.001489739],"genre_scores_gemma":[0.9986176,0.0003891659,0.0003082036,0.00004785112,0.00004702806,0.000006215769,0.0002172609,0.000003591892,0.0003630917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003833676,"threshold_uncertainty_score":0.01282495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07485098648915137,"score_gpt":0.360680094750996,"score_spread":0.2858291082618447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}